Tunable metal–organic frameworks assist in catalyzing DNAzymes with amplification platforms for biomedical applications

X Zhu, J Xu, G Ling, P Zhang - Chemical Society Reviews, 2023 - pubs.rsc.org
Various binding modes of tunable metal organic frameworks (MOFs) and functional
DNAzymes (Dzs) synergistically catalyze the emergence of abundant functional …

MOF-based micro/nanomotors (MOFtors): Recent progress and challenges

H Yang, L Wang, X Huang - Coordination Chemistry Reviews, 2023 - Elsevier
Micro/nanomotors (MNMs) are burgeoning micro/nanoscale devices with plentiful
applications ranging from biomedicine to environmental remediation. However, some urgent …

Biomimetic Nanozyme-Decorated Hydrogels with H2O2-Activated Oxygenation for Modulating Immune Microenvironment in Diabetic Wound

Y Zhao, D Wang, T Qian, J Zhang, Z Li, Q Gong… - ACS …, 2023 - ACS Publications
Diabetic foot ulcers (DFUs) remain a devastating threat to human health. While hydrogels
are promising systems for DFU-based wound management, their effectiveness is often …

Target‐Specific Bioorthogonal Reactions for Precise Biomedical Applications

Z Liu, M Sun, W Zhang, J Ren, X Qu - Angewandte Chemie, 2023 - Wiley Online Library
Bioorthogonal chemistry is a promising toolbox for dissecting biological processes in the
native environment. Recently, bioorthogonal reactions have attracted considerable attention …

[HTML][HTML] Multifunctional nanomedicines-enabled chemodynamic-synergized multimodal tumor therapy via Fenton and Fenton-like reactions

H Gao, Z Cao, H Liu, L Chen, Y Bai, Q Wu, X Yu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Chemodynamic therapy (CDT) is well-known for using the tumor microenvironment to
activate the Fenton reaction or Fenton-like reaction to generate strong oxidative hydroxyl …

Nanozyme-activating prodrug therapies: A review

Y Wu, W Chen, C Wang, D Xing - Chinese Chemical Letters, 2023 - Elsevier
Enzyme prodrug therapies (EPTs) have been intensively explored as attractive approaches
to selective activation of systemically administered benign prodrugs by the exogenous …

Biodegradable Ferric Phosphate Nanocarriers with Tumor‐Specific Activation and Glutathione Depletion for Tumor Self‐Enhanced Ferroptosis and Chemotherapy

Y Li, W Fan, X Gu, S Liu, T He, S Gou… - Advanced Functional …, 2024 - Wiley Online Library
Ferroptosis is a regulatory cell death that is dependent on iron‐mediated lipid peroxidation
and cell membrane damage. The use of iron‐based nanocarriers to activate ferroptosis is of …

Cell death pathway regulation by functional nanomedicines for robust antitumor immunity

Y Li, Y Guo, K Zhang, R Zhu, X Chen… - Advanced …, 2024 - Wiley Online Library
Cancer immunotherapy has become a mainstream cancer treatment over traditional
therapeutic modes. Cancer cells can undergo programmed cell death including ferroptosis …

Camptothecin-based prodrug nanomedicines for cancer therapy

H Jiang, RS Zhang, C Wang, J Yu, Z Guo - Nanoscale, 2023 - pubs.rsc.org
Camptothecin (CPT) is a cytotoxic alkaloid that attenuates the replication cancer cells via
blocking DNA topoisomerase 1. Despite its encouraging and wide spectrum antitumour …

Fenton chemistry activation in metal-organic frameworks for synergistic bacteria eradication

J Qin, J Su, H Li, L Zhang, K Jiang - Chemical Engineering Journal, 2024 - Elsevier
The development of novel antibacterial strategies as alternatives to antibiotics is of great
significance but remains considerable challenges due to the lack of safe, effective, and …