Interleukin-18 (IL-18) is a potent pro-inflammatory cytokine involved in host defense against
infections and regulates the innate and acquired immune response. IL-18 is produced by …

Psoriasis is a chronic inflammatory skin disorder, and current treatments include topical
therapies, phototherapy, systemic immune modulators, and biologics, aiming to alleviate …

Over the past three decades, many methods have been developed to evaluate levels of
biomarkers in autoimmune diseases. Early investigations have shown that some biomarkers …

Transplanting aged human skin onto young SCID/beige mice morphologically rejuvenates
the xenotransplants. This is accompanied by angiogenesis, epidermal repigmentation, and …

Rationale Psoriasis is a chronic inflammatory skin disease involving different cytokines and
chemokines. Objectives Here we use single‐cell transcriptomic analyses to identify relevant …

Background Recent knowledge of psoriasis pathogenesis has led to the development of
selective drugs. Among these, brodalumab is a monoclonal antibody targeting the …

Although biomarker candidates associated with psoriasis have been suggested, those for
predicting the risk of cardiovascular disease (CVD) early in patients with psoriasis are …

Kidney diseases with kidney failure or damage, such as chronic kidney disease (CKD) and
acute kidney injury (AKI), are common clinical problems worldwide and have rapidly …

Obesity and diabetes are independent risk factors for death during sepsis. S100A8, an
alarmin, is related to inflammation, obesity, and diabetes. Here, we examine the role of …

Immunologically targeted therapies have revolutionized the treatment of inflammatory
dermatoses, including atopic dermatitis and psoriasis. Although immunologic biomarkers …