Recurrent implantation failure: definition and management

C Coughlan, W Ledger, Q Wang, F Liu… - Reproductive …, 2014 - Elsevier
Recurrent implantation failure refers to failure to achieve a clinical pregnancy after transfer of
at least four good-quality embryos in a minimum of three fresh or frozen cycles in a woman …

[HTML][HTML] Male subfertility and oxidative stress

EPP Evans, JTM Scholten, A Mzyk… - Redox biology, 2021 - Elsevier
To date 15% of couples are suffering from infertility with 45–50% of males being
responsible. With an increase in paternal age as well as various environmental and lifestyle …

[HTML][HTML] Sperm DNA fragmentation: mechanisms of origin, impact on reproductive outcome, and analysis

D Sakkas, JG Alvarez - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To review the mechanisms responsible for DNA fragmentation in human
sperm, including those occurring during spermatogenesis and transport through the …

Clinical relevance of oxidative stress in male factor infertility: an update

A Agarwal, K Makker, R Sharma - American journal of …, 2008 - Wiley Online Library
Male factor has been considered a major contributory factor to infertility. Along with the
conventional causes for male infertility such as varicocele, cryptorchidism, infections …

[HTML][HTML] Comparison of reproductive outcome in oligozoospermic men with high sperm DNA fragmentation undergoing intracytoplasmic sperm injection with …

SC Esteves, F Sánchez-Martín, P Sánchez-Martín… - Fertility and sterility, 2015 - Elsevier
Objective To investigate the effectiveness of intracytoplasmic sperm injection (ICSI) using
testicular sperm as a strategy to overcome infertility in men with high sperm DNA …

Sperm selection in assisted reproduction: A review of established methods and cutting-edge possibilities

G Marzano, MS Chiriacò, E Primiceri… - Biotechnology …, 2020 - Elsevier
Male infertility often involves idiopathic or unknown causes, leading to an increasing
demand for assisted reproduction technologies (ART). Conventional sperm sorting …

[HTML][HTML] Sperm viability, apoptosis, and intracellular reactive oxygen species levels in human spermatozoa before and after induction of oxidative stress

RZ Mahfouz, SS du Plessis, N Aziz, R Sharma… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To investigate sperm viability, incidence of apoptosis, and intracellular basal
and induced reactive oxygen species (ROS) in sperm fractions. DESIGN: Prospective …

Effects of advanced selection methods on sperm quality and ART outcome: a systematic review

TM Said, JA Land - Human reproduction update, 2011 - academic.oup.com
BACKGROUND Current routine semen preparation techniques do not inclusively target all
intrinsic sperm characteristics that may impact the fertilization potential. In order to address …

[HTML][HTML] An update on oxidative damage to spermatozoa and oocytes

CS Opuwari, RR Henkel - BioMed research international, 2016 - hindawi.com
On the one hand, reactive oxygen species (ROS) are mandatory mediators for essential
cellular functions including the function of germ cells (oocytes and spermatozoa) and …

[HTML][HTML] Sperm preparation: state-of-the-art—physiological aspects and application of advanced sperm preparation methods

R Henkel - Asian journal of andrology, 2012 - ncbi.nlm.nih.gov
For assisted reproduction technologies (ART), numerous techniques were developed to
isolate spermatozoa capable of fertilizing oocytes. While early methodologies only focused …