[HTML][HTML] Stress and telomere shortening: Insights from cellular mechanisms

J Lin, E Epel - Ageing research reviews, 2022 - Elsevier
Short telomeres confer risk of degenerative diseases. Chronic psychological stress can lead
to disease through many pathways, and research from in vitro studies to human longitudinal …

Mediterranean diet as an antioxidant: the impact on metabolic health and overall wellbeing

KV Gantenbein, C Kanaka-Gantenbein - Nutrients, 2021 - mdpi.com
It has been established, worldwide, that non-communicable diseases such as obesity,
diabetes, metabolic syndrome, and cardiovascular events account for a high percentage of …

Association between COVID‐19 and telomere length: a bidirectional Mendelian randomization study

D Huang, S Lin, J He, Q Wang… - Journal of medical …, 2022 - Wiley Online Library
Several traditional observational studies suggested an association between COVID‐19 and
leukocyte telomere length (LTL), a biomarker for biological age. However, whether there …

G-quadruplex DNA: a novel target for drug design

FY Teng, ZZ Jiang, M Guo, XZ Tan, F Chen… - Cellular and Molecular …, 2021 - Springer
Abstract G-quadruplex (G4) DNA is a type of quadruple helix structure formed by a
continuous guanine-rich DNA sequence. Emerging evidence in recent years authenticated …

Evidence for biological age acceleration and telomere shortening in COVID-19 survivors

A Mongelli, V Barbi, M Gottardi Zamperla… - International journal of …, 2021 - mdpi.com
The SARS-CoV-2 infection determines the COVID-19 syndrome characterized, in the worst
cases, by severe respiratory distress, pulmonary and cardiac fibrosis, inflammatory cytokine …

[HTML][HTML] Shortened leukocyte telomere length is associated with glycemic progression in type 2 diabetes: a prospective and mendelian randomization analysis

F Cheng, AO Luk, M Shi, C Huang, G Jiang… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE Several studies support associations between relative leukocyte telomere
length (rLTL), a biomarker of biological aging and type 2 diabetes. This study investigates …

Leukocyte telomere length in children born following blastocyst-stage embryo transfer

C Wang, Y Gu, J Zhou, J Zang, X Ling, H Li, L Hu… - Nature medicine, 2022 - nature.com
Perinatal and childhood adverse outcomes associated with assisted reproductive
technology (ART) has been reported, but it remains unknown whether the initial leukocyte …

Biological ageing and the risks of all-cause and cause-specific mortality among people with diabetes: a prospective cohort study

L Chen, X Yin, Y Zhao, H Chen, T Tan… - J Epidemiol Community …, 2022 - jech.bmj.com
Background The aetiology of diabetes is complex with limited treatment strategies. Growing
animal studies have shown that targeted antiageing can improve the outcomes of diabetes …

Translation of polymeric microneedles for treatment of human diseases: Recent trends, Progress, and Challenges

PR Yadav, MN Munni, L Campbell, G Mostofa… - Pharmaceutics, 2021 - mdpi.com
The ongoing search for biodegradable and biocompatible microneedles (MNs) that are
strong enough to penetrate skin barriers, easy to prepare, and can be translated for clinical …

Skeletal muscle as a treatment target for older adults with diabetes mellitus: The importance of a multimodal intervention based on functional category

T Omura, A Araki - Geriatrics & Gerontology International, 2022 - Wiley Online Library
Although the lifespan of people with diabetes has increased in many countries, the age‐
related increase in comorbidities (sarcopenia, frailty and disabilities) and diabetic …