The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

Anosmia, the loss of smell, is a common and often the sole symptom of COVID-19. The onset
of the sequence of pathobiological events leading to olfactory dysfunction remains obscure …

Emerging evidence points toward an intricate relationship between the pandemic of
coronavirus disease 2019 (COVID-19) and diabetes. While preexisting diabetes is …

Despite the unprecedented effort of the scientific community, the novel SARS-CoV-2 virus
has infected more than 46 million people worldwide, killing over one million two hundred …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human adaptation resulted
in distinct lineages with enhanced transmissibility called variants of concern (VOCs) …

The upper respiratory tract is compromised in the early period of COVID-19, but SARS-CoV-
2 tropism at the cellular level is not fully defined. Unlike recent single-cell RNA-Seq analyses …

How SARS-CoV-2 penetrates the airway barrier of mucus and periciliary mucins to infect
nasal epithelium remains unclear. Using primary nasal epithelial organoid cultures, we …

Increasing evidence demonstrated that the expression of Angiotensin I-Converting Enzyme
type 2 (ACE2) is a necessary step for SARS-CoV-2 infection permissiveness. In light of the …

COVID-19 has different clinical stages, and effective therapy depends on the location and
extent of the infection. The purpose of this review is to provide a background for …