[HTML][HTML] An updated review summarizing the anticancer efficacy of melittin from bee venom in several models of human cancers
Apitherapy (using bee products) has gained broad recognition in cancer therapeutics
globally. Honeybee venom has a broad range of biological potential, and its utilization is …
globally. Honeybee venom has a broad range of biological potential, and its utilization is …
[HTML][HTML] Pharmacological effects and mechanisms of bee venom and its main components: Recent progress and perspective
P Shi, S Xie, J Yang, Y Zhang, S Han, S Su… - Frontiers in …, 2022 - frontiersin.org
Bee venom (BV), a type of defensive venom, has been confirmed to have favorable
activities, such as anti-tumor, neuroprotective, anti-inflammatory, analgesic, anti-infectivity …
activities, such as anti-tumor, neuroprotective, anti-inflammatory, analgesic, anti-infectivity …
[HTML][HTML] Pharmacological properties and therapeutic potential of honey bee venom
Honey bee venom (BV) is a valuable product, and has a wide range of biological effects,
and its use is rapidly increasing in apitherapy. Therefore, the current study, we reviewed the …
and its use is rapidly increasing in apitherapy. Therefore, the current study, we reviewed the …
[HTML][HTML] Can bee venom be used as anticancer agent in modern medicine?
A Małek, M Strzemski, J Kurzepa, J Kurzepa - Cancers, 2023 - mdpi.com
Simple Summary The beneficial effects of natural substances that have been used in
medicine for many years require both scientific confirmation and recognition of the …
medicine for many years require both scientific confirmation and recognition of the …
[HTML][HTML] Beehive products as antibacterial agents: A review
RA Nader, R Mackieh, R Wehbe, D El Obeid… - Antibiotics, 2021 - mdpi.com
Honeybees are one of the most marvelous and economically beneficial insects. As
pollinators, they play a vital role in every aspect of the ecosystem. Beehive products have …
pollinators, they play a vital role in every aspect of the ecosystem. Beehive products have …
[HTML][HTML] The current landscape of the antimicrobial peptide melittin and its therapeutic potential
HQ Zhang, C Sun, N Xu, W Liu - Frontiers in Immunology, 2024 - frontiersin.org
Melittin, a main component of bee venom, is a cationic amphiphilic peptide with a linear α-
helix structure. It has been reported that melittin can exert pharmacological effects, such as …
helix structure. It has been reported that melittin can exert pharmacological effects, such as …
[HTML][HTML] Evaluation of anti-cancer effects of carnosine and melittin-loaded niosomes in MCF-7 and MDA-MB-231 breast cancer cells
MMA Hussein, A Abdelfattah-Hassan… - Frontiers in …, 2023 - frontiersin.org
Background: We investigated the anti-cancer effect of carnosine-loaded niosomes (Car-NIO)
and melittin-loaded niosomes (Mel-NIO) with olaparib in breast cancer cell lines (MCF-7 and …
and melittin-loaded niosomes (Mel-NIO) with olaparib in breast cancer cell lines (MCF-7 and …
[HTML][HTML] Bee Venom and Its Two Main Components—Melittin and Phospholipase A2—As Promising Antiviral Drug Candidates
C Yaacoub, R Wehbe, R Roufayel, Z Fajloun… - Pathogens, 2023 - mdpi.com
Viruses are known to infect most types of organisms. In humans, they can cause several
diseases that range from mild to severe. Although many antiviral therapies have been …
diseases that range from mild to severe. Although many antiviral therapies have been …
[HTML][HTML] Bee venom-loaded EGFR-targeting peptide-coupled chitosan nanoparticles for effective therapy of hepatocellular carcinoma by inhibiting EGFR-mediated …
S Abdulmalek, N Mostafa, M Gomaa, M El‑Kersh… - PLoS …, 2022 - journals.plos.org
Hepatocellular carcinoma (HCC) is one of the world's most risky diseases due to the lack of
clear and cost-effective therapeutic targets. Currently, the toxicity of conventional …
clear and cost-effective therapeutic targets. Currently, the toxicity of conventional …
[HTML][HTML] Melittin inhibits the proliferation migration and invasion of HCC cells by regulating ADAMTS9-AS2 demethylation
C Lv, J Chen, F Huang, F Fang, B Li - Toxicon, 2023 - Elsevier
Background Melittin (MEL) has been reported to exhibit anti-cancer effects in vitro against
several types of cancer. Long non-coding RNA (lncRNA) ADAMTS9-AS2 can be used as a …
several types of cancer. Long non-coding RNA (lncRNA) ADAMTS9-AS2 can be used as a …