In recent years, stem cell therapy has become a very promising and advanced scientific
research topic. The development of treatment methods has evoked great expectations. This …

Review on tissue repair and M1-like to M2a-like macrophages, exhibiting important
differences from in vitro phenotypes. Mp are crucial for tissue repair and regeneration but …

Tumor metastases are responsible for approximately 90% of all cancer-related deaths.
Although many patients can be cured, in the US and UK, cancer still causes 730,000 deaths …

Human skin comprises stratified squamous epithelium and dermis with various stromal cells
and the extracellular matrix (ECM). The basement membrane (BM), a thin layer at the top of …

Mitral valve prolapse (MVP) is a common human phenotype, yet little is known about the
pathogenesis of this condition. MVP can occur in the context of genetic syndromes, including …

Abstract Tumor-associated macrophages (TAMs), as a major and essential component of
tumor microenvironment (TME), play a critical role in orchestrating pancreatic cancer (PaC) …

Objective Pancreatic cancer is associated with an abundant stromal reaction leading to
immune escape and tumour growth. This massive stroma drives the immune escape in the …

TGFBIp/βig-h3 protein is an extracellular matrix molecule initially cloned from human
adenocarcinoma cells treated with TGF-β. Its precise function remains obscure but a number …

Tissue repair and regeneration is an interdisciplinary field focusing on development of
biological and bioactive substitutes. Chitosan is a natural polysaccharide exhibiting …

Metastasis, the major cause of cancer death, is a multistep process that requires interactions
between cancer cells and stromal cells and between cancer cells and extracellular matrix …