[HTML][HTML] Stem cells: past, present, and future
W Zakrzewski, M Dobrzyński, M Szymonowicz… - Stem cell research & …, 2019 - Springer
In recent years, stem cell therapy has become a very promising and advanced scientific
research topic. The development of treatment methods has evoked great expectations. This …
research topic. The development of treatment methods has evoked great expectations. This …
Macrophage phenotypes during tissue repair
ML Novak, TJ Koh - Journal of leukocyte biology, 2013 - academic.oup.com
Review on tissue repair and M1-like to M2a-like macrophages, exhibiting important
differences from in vitro phenotypes. Mp are crucial for tissue repair and regeneration but …
differences from in vitro phenotypes. Mp are crucial for tissue repair and regeneration but …
Molecular networks that regulate cancer metastasis
D Spano, C Heck, P De Antonellis, G Christofori… - Seminars in cancer …, 2012 - Elsevier
Tumor metastases are responsible for approximately 90% of all cancer-related deaths.
Although many patients can be cured, in the US and UK, cancer still causes 730,000 deaths …
Although many patients can be cured, in the US and UK, cancer still causes 730,000 deaths …
Spatially resolved proteomic map shows that extracellular matrix regulates epidermal growth
J Li, J Ma, Q Zhang, H Gong, D Gao, Y Wang… - Nature …, 2022 - nature.com
Human skin comprises stratified squamous epithelium and dermis with various stromal cells
and the extracellular matrix (ECM). The basement membrane (BM), a thin layer at the top of …
and the extracellular matrix (ECM). The basement membrane (BM), a thin layer at the top of …
TGF-β–dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome
CM Ng, A Cheng, LA Myers… - The Journal of …, 2004 - Am Soc Clin Investig
Mitral valve prolapse (MVP) is a common human phenotype, yet little is known about the
pathogenesis of this condition. MVP can occur in the context of genetic syndromes, including …
pathogenesis of this condition. MVP can occur in the context of genetic syndromes, including …
[HTML][HTML] A novel role of TGFBI in macrophage polarization and macrophage-induced pancreatic cancer growth and therapeutic resistance
J Zhou, N Lyu, Q Wang, M Yang, ET Kimchi, K Cheng… - Cancer letters, 2023 - Elsevier
Abstract Tumor-associated macrophages (TAMs), as a major and essential component of
tumor microenvironment (TME), play a critical role in orchestrating pancreatic cancer (PaC) …
tumor microenvironment (TME), play a critical role in orchestrating pancreatic cancer (PaC) …
Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer
D Goehrig, J Nigri, R Samain, Z Wu, P Cappello… - Gut, 2019 - gut.bmj.com
Objective Pancreatic cancer is associated with an abundant stromal reaction leading to
immune escape and tumour growth. This massive stroma drives the immune escape in the …
immune escape and tumour growth. This massive stroma drives the immune escape in the …
TGFBIp/βig-h3 protein: A versatile matrix molecule induced by TGF-β
TGFBIp/βig-h3 protein is an extracellular matrix molecule initially cloned from human
adenocarcinoma cells treated with TGF-β. Its precise function remains obscure but a number …
adenocarcinoma cells treated with TGF-β. Its precise function remains obscure but a number …
Chitosan-based biomaterials for tissue repair and regeneration
X Liu, L Ma, Z Mao, C Gao - Chitosan for biomaterials II, 2011 - Springer
Tissue repair and regeneration is an interdisciplinary field focusing on development of
biological and bioactive substitutes. Chitosan is a natural polysaccharide exhibiting …
biological and bioactive substitutes. Chitosan is a natural polysaccharide exhibiting …
Extracellular matrix protein βig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation
C Ma, Y Rong, DR Radiloff, MB Datto… - Genes & …, 2008 - genesdev.cshlp.org
Metastasis, the major cause of cancer death, is a multistep process that requires interactions
between cancer cells and stromal cells and between cancer cells and extracellular matrix …
between cancer cells and stromal cells and between cancer cells and extracellular matrix …