Plague vaccines: new developments in an ongoing search
JA Rosenzweig, EK Hendrix, AK Chopra - Applied Microbiology and …, 2021 - Springer
As the reality of pandemic threats challenges humanity, exemplified during the ongoing
SARS-CoV-2 infections, the development of vaccines targeting these etiological agents of …
SARS-CoV-2 infections, the development of vaccines targeting these etiological agents of …
Plague prevention and therapy: perspectives on current and future strategies
R Rosario-Acevedo, SS Biryukov, JA Bozue, CK Cote - Biomedicines, 2021 - mdpi.com
Plague, caused by the bacterial pathogen Yersinia pestis, is a vector-borne disease that has
caused millions of human deaths over several centuries. Presently, human plague infections …
caused millions of human deaths over several centuries. Presently, human plague infections …
Induction of protective antiplague immune responses by self-adjuvanting bionanoparticles derived from engineered Yersinia pestis
ABSTRACT A Yersinia pestis mutant synthesizing an adjuvant form of lipid A
(monophosphoryl lipid A, MPLA) displayed increased biogenesis of bacterial outer …
(monophosphoryl lipid A, MPLA) displayed increased biogenesis of bacterial outer …
Pneumonic Plague Protection Induced by a Monophosphoryl Lipid A Decorated Yersinia Outer‐Membrane‐Vesicle Vaccine
S Majumder, S Das, P Li, N Yang, H Dellario, H Sui… - Small, 2024 - Wiley Online Library
A new Yersinia pseudotuberculosis mutant strain, YptbS46, carrying the lpxE insertion and
pmrF‐J deletion is constructed and shown to exclusively produce monophosphoryl lipid A …
pmrF‐J deletion is constructed and shown to exclusively produce monophosphoryl lipid A …
Yersinia pestis Antigen F1 but Not LcrV Induced Humoral and Cellular Immune Responses in Humans Immunized with Live Plague Vaccine—Comparison of …
VA Feodorova, AM Lyapina, MA Khizhnyakova… - Vaccines, 2020 - mdpi.com
The recent progress in immunoinformatics provided the basis for an accelerated
development of target-specific peptide vaccines as an alternative to the traditional vaccine …
development of target-specific peptide vaccines as an alternative to the traditional vaccine …
A new generation needle-and adjuvant-free trivalent plague vaccine utilizing adenovirus-5 nanoparticle platform
PB Kilgore, J Sha, JA Andersson, VL Motin, AK Chopra - npj Vaccines, 2021 - nature.com
A plague vaccine with a fusion cassette of Y scF, F 1, and Lcr V encoding genes in an
adenovirus-5 vector (rAd5-YFV) is evaluated for efficacy and immune responses in mice …
adenovirus-5 vector (rAd5-YFV) is evaluated for efficacy and immune responses in mice …
Protection Induced by Oral Vaccination with a Recombinant Yersinia pseudotuberculosis Delivering Yersinia pestis LcrV and F1 Antigens in Mice and Rats against …
ABSTRACT A newly attenuated Yersinia pseudotuberculosis strain (designated Yptb1) with
triple mutation Δ asd Δ yopK Δ yopJ and chromosomal insertion of the Y. pestis caf1R-caf1M …
triple mutation Δ asd Δ yopK Δ yopJ and chromosomal insertion of the Y. pestis caf1R-caf1M …
Secretory system components as potential prophylactic targets for bacterial pathogens
W Swietnicki - Biomolecules, 2021 - mdpi.com
Bacterial secretory systems are essential for virulence in human pathogens. The systems
have become a target of alternative antibacterial strategies based on small molecules and …
have become a target of alternative antibacterial strategies based on small molecules and …
Impact of MgtC on the Fitness of Yersinia pseudotuberculosis
P Li, H Wang, W Sun, J Ding - Pathogens, 2023 - mdpi.com
Yersinia pseudotuberculosis is an extracellular foodborne pathogen and usually causes self-
limiting diarrhea in healthy humans. MgtC is known as a key subversion factor that …
limiting diarrhea in healthy humans. MgtC is known as a key subversion factor that …
Recent Advancements and Novel Approaches Contributing to the Present Arsenal of Prophylaxis and Treatment Strategies Against Category A Bacterial Biothreat …
A Patnaik, SK Rai, RK Dhaked - Indian journal of microbiology, 2023 - Springer
Bacterial pathogens have always been a part of the ecosystem in which we thrive. Some
pathogens have caused deadly outbreaks in the past and have been exploited as an agent …
pathogens have caused deadly outbreaks in the past and have been exploited as an agent …