Lys49 myotoxins, secreted phospholipase A2-like proteins of viperid venoms: A comprehensive review

B Lomonte - Toxicon, 2023 - Elsevier
Muscle necrosis is a potential clinical complication of snakebite envenomings, which in
severe cases can lead to functional or physical sequelae such as disability or amputation …

From fangs to pharmacology: the future of snakebite envenoming therapy

AH Laustsen, M Engmark, C Milbo… - Current …, 2016 - ingentaconnect.com
The snake is the symbol of medicine due to its association with Asclepius, the Greek God of
medicine, and so with good reasons. More than 725 species of venomous snakes have …

Molecular dissection of cobra venom highlights heparinoids as an antidote for spitting cobra envenoming

TY Du, SR Hall, F Chung, S Kurdyukov… - Science Translational …, 2024 - science.org
Snakebites affect about 1.8 million people annually. The current standard of care involves
antibody-based antivenoms, which can be difficult to access and are generally not effective …

[HTML][HTML] Clinical management of snakebite envenoming: future perspectives

M Hamza, C Knudsen, CA Gnanathasan, W Monteiro… - Toxicon: X, 2021 - Elsevier
Snakebite envenoming is a major cause of morbidity and mortality in rural communities
throughout the tropics. Generally, the main clinical features of snakebites are local swelling …

Antivenoms for snakebite envenomings

J Maria Gutierrez, G León, B Lomonte… - Inflammation & Allergy …, 2011 - ingentaconnect.com
Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming.
Antivenoms are manufactured by immunizing animals, usually horses, with venoms from a …

Perspective on the therapeutics of anti-snake venom

I Gómez-Betancur, V Gogineni, A Salazar-Ospina… - Molecules, 2019 - mdpi.com
Snakebite envenomation is a life-threatening disease that was recently re-included as a
neglected tropical disease (NTD), affecting millions of people in tropical and subtropical …

Plant-derived toxin inhibitors as potential candidates to complement antivenom treatment in snakebite envenomations

AAX Adrião, AO Dos Santos, EJSP de Lima… - Frontiers in …, 2022 - frontiersin.org
Snakebite envenomations (SBEs) are a neglected medical condition of global importance
that mainly affect the tropical and subtropical regions. Clinical manifestations include pain …

Inhibitory effects of hydroethanolic leaf extracts of Kalanchoe brasiliensis and Kalanchoe pinnata (Crassulaceae) against local effects induced by Bothrops jararaca …

JM Fernandes, J Felix-Silva, LM da Cunha… - PloS one, 2016 - journals.plos.org
The species Kalanchoe brasiliensis and Kalanchoe pinnata, both known popularly as
“Saião,” are used interchangeably in traditional medicine for their antiophidic properties …

Ethnopharmacological survey of medicinal plants used by traditional healers and indigenous people in Chittagong Hill Tracts, Bangladesh, for the treatment of …

MF Kadir, JR Karmoker, MR Alam… - Evidence‐Based …, 2015 - Wiley Online Library
Snakebites are common in tropical countries like Bangladesh where most snakebite victims
dwell in rural areas. Among the management options after snakebite in Bangladesh, snake …

Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA2 Inhibition

JI Dos Santos, FF Cardoso, AM Soares… - PloS one, 2011 - journals.plos.org
Snakebite envenoming is an important public health problem in many tropical and
subtropical countries, and is considered a neglected tropical disease by the World Health …