Meningococcal disease

NE Rosenstein, BA Perkins, DS Stephens… - New England journal …, 2001 - Mass Medical Soc
Reports of illness resembling meningococcal disease date back to the 16th century. The
description reported by Vieusseux in 1805 is generally thought to be the first definitive …

Neisseria meningitidis: Biology, Microbiology, and Epidemiology

NG Rouphael, DS Stephens - Neisseria meningitidis: advanced methods …, 2012 - Springer
Neisseria meningitidis (the meningococcus) causes significant morbidity and mortality in
children and young adults worldwide through epidemic or sporadic meningitis and/or …

Pathogenic neisseriae: surface modulation, pathogenesis and infection control

M Virji - Nature Reviews Microbiology, 2009 - nature.com
Although renowned as a lethal pathogen, Neisseria meningitidis has adapted to be a
commensal of the human nasopharynx. It shares extensive genetic and antigenic similarities …

Pathogenesis of Afa/Dr Diffusely Adhering Escherichia coli

AL Servin - Clinical microbiology reviews, 2005 - Am Soc Microbiol
Over the last few years, dramatic increases in our knowledge about diffusely adhering
Escherichia coli (DAEC) pathogenesis have taken place. The typical class of DAEC includes …

Interactions of Pathogenic Neisseriae with Epithelial Cell Membranes

AJ Merz, M So - Annual review of cell and developmental …, 2000 - annualreviews.org
▪ Abstract The closely related bacterial pathogens Neisseria gonorrhoeae (gonococci, GC)
and N. meningitidis (meningococci, MC) initiate infection at human mucosal epithelia …

Cellular and molecular biology of Neisseria meningitidis colonization and invasive disease

DJ Hill, NJ Griffiths, E Borodina, M Virji - Clinical science, 2010 - portlandpress.com
The human species is the only natural host of Neisseria meningitidis, an important cause of
bacterial meningitis globally, and, despite its association with devastating diseases, N …

The sweet tooth of bacteria: common themes in bacterial glycoconjugates

HLP Tytgat, S Lebeer - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
Humans have been increasingly recognized as being superorganisms, living in close
contact with a microbiota on all their mucosal surfaces. However, most studies on the human …

Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis

EA Catton, DA Bonsor, C Herrera… - nature …, 2023 - nature.com
Life-threatening bacterial infections in women after childbirth, known as puerperal sepsis,
resulted in classical epidemics and remain a global health problem. While outbreaks of …

Opa proteins and CEACAMs: pathways of immune engagement for pathogenic Neisseria

M Sadarangani, AJ Pollard… - FEMS microbiology …, 2011 - academic.oup.com
Neisseria meningitidis and Neisseria gonorrhoeae are globally important pathogens, which
in part owe their success to their ability to successfully evade human immune responses …

CEACAM1 structure and function in immunity and its therapeutic implications

WM Kim, YH Huang, A Gandhi, RS Blumberg - Seminars in immunology, 2019 - Elsevier
The type I membrane protein receptor carcinoembryonic antigen-related cell adhesion
molecule 1 (CEACAM1) distinctively exhibits significant alternative splicing that allows for …