[HTML][HTML] Therapeutic implications of caffeic acid in cancer and neurological diseases

M Alam, S Ahmed, AM Elasbali, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA
and its derivatives have been used for many centuries due to their natural healing and …

[HTML][HTML] Targeting the JAK/STAT signaling pathway using phytocompounds for cancer prevention and therapy

S Bose, S Banerjee, A Mondal, U Chakraborty… - Cells, 2020 - mdpi.com
Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …

Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (Mpro) of SARS-CoV-2 and inhibit its activity

V Kumar, JK Dhanjal, SC Kaul, R Wadhwa… - Journal of …, 2021 - Taylor & Francis
The recent novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2/2019-nCoV) has caused a large number of deaths around the globe. There is an …

An insight into anticancer effect of propolis and its constituents: a review of molecular mechanisms

P Elumalai, N Muninathan… - Evidence‐Based …, 2022 - Wiley Online Library
Propolis is a natural compound collected by honeybees from different parts of plants.
Honeybees produce a sticky component besides honey by mixing the tree resin and other …

[HTML][HTML] Biological actions and molecular effects of resveratrol, pterostilbene, and 3′-hydroxypterostilbene

HY Tsai, CT Ho, YK Chen - Journal of food and drug analysis, 2017 - Elsevier
Stilbenes are a class of polyphenolic compounds, naturally found in a wide variety of dietary
sources such as grapes, berries, peanuts, red wine, and some medicinal plants. There are …

Therapeutic effects and safe uses of plant-derived polyphenolic compounds in cardiovascular diseases: a review

BS Alotaibi, M Ijaz, M Buabeid, ZJ Kharaba… - Drug design …, 2021 - Taylor & Francis
Polyphenols have long been recognized as health-promoting entities, including beneficial
effects on cardiovascular disease, but their reputation has been boosted recently following a …

The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase …

İ Gülçin, A Scozzafava, CT Supuran… - Journal of enzyme …, 2016 - Taylor & Francis
Caffeic acid phenethyl ester (CAPE) is an active component of honeybee propolis extracts.
Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread and intensively studied …

Hybrid molecules based on caffeic acid as potential therapeutics: A focused review

X Zhao, Z Liu, H Liu, J Guo, S Long - European Journal of Medicinal …, 2022 - Elsevier
Caffeic acid-based compounds possess a high degree of structural diversity and show a
variety of pharmacological properties, providing a useful framework for the discovery of new …

Emerging adjuvant therapy for cancer: propolis and its constituents

S Patel - Journal of dietary supplements, 2016 - Taylor & Francis
Propolis is a bee-metabolized resinous substance (bee glue) from plant sap and gums. It
has been in usage as a healing agent since antiquity, yet has not garnered global popularity …

Investigation of the anti-inflammatory effects of caffeic acid phenethyl ester in a model of λ-Carrageenan–induced paw edema in rats

HS Semis, C Gur, M Ileriturk, O Kaynar… - Human & …, 2021 - journals.sagepub.com
In the present study, it is aimed to evaluate the effects of caffeic acid phenethyl ester (CAPE)
against acute paw inflammation induced by carragenan (Carr) at macro and micro levels …