Activation of microglia and astrocytes: a roadway to neuroinflammation and Alzheimer's disease

D Kaur, V Sharma, R Deshmukh - Inflammopharmacology, 2019 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease that is of high importance to the
neuroscience world, yet the complex pathogenicity is not fully understood. Inflammation is …

Neurotransmitter systems in the etiology of major neurological disorders: Emerging insights and therapeutic implications

M Nimgampalle, H Chakravarthy, S Sharma… - Ageing Research …, 2023 - Elsevier
Neurotransmitters serve as chemical messengers playing a crucial role in information
processing throughout the nervous system, and are essential for healthy physiological and …

[HTML][HTML] Clinical trials in Alzheimer's disease: a hurdle in the path of remedy

AE Oxford, ES Stewart, TT Rohn - International Journal of …, 2020 - hindawi.com
Human clinical trials seek to ameliorate the disease states and symptomatic progression of
illnesses that, as of yet, are largely untreatable according to clinical standards. Ideally …

Three-dimensional brain-on-a-chip with an interstitial level of flow and its application as an in vitro model of Alzheimer's disease

JS Park, BK Lee, GS Jeong, JK Hyun, CJ Lee, SH Lee - Lab on a Chip, 2015 - pubs.rsc.org
There has been a growing need for in vitro models of neurodegenerative diseases such as
Alzheimer's disease that would enable a better understanding of etiology and faster …

Glial cells in Alzheimer's disease: From neuropathological changes to therapeutic implications

MS Uddin, LW Lim - Ageing research reviews, 2022 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …

Altered motor cortex physiology and dysexecutive syndrome in patients with fatigue and cognitive difficulties after mild COVID‐19

P Ortelli, D Ferrazzoli, L Sebastianelli… - European journal of …, 2022 - Wiley Online Library
Background and purpose Fatigue and cognitive difficulties are reported as the most
frequently persistent symptoms in patients after mild SARS‐CoV‐2 infection. An extensive …

What electrophysiology tells us about Alzheimer's disease: a window into the synchronization and connectivity of brain neurons

C Babiloni, K Blinowska, L Bonanni, A Cichocki… - Neurobiology of …, 2020 - Elsevier
Electrophysiology provides a real-time readout of neural functions and network capability in
different brain states, on temporal (fractions of milliseconds) and spatial (micro, meso, and …

Glutamate system, amyloid β peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology

TJ Revett, GB Baker, J Jhamandas, S Kar - Journal of Psychiatry and …, 2013 - jpn.ca
Alzheimer disease is the most prevalent form of dementia globally and is characterized
premortem by a gradual memory loss and deterioration of higher cognitive functions and …

[HTML][HTML] Is dopamine involved in Alzheimer's disease?

A Martorana, G Koch - Frontiers in aging neuroscience, 2014 - frontiersin.org
Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive
cognitive decline and dementia. Recent advances indicate that AD pathogenesis appears …

The significance of the cholinergic system in the brain during aging and in Alzheimer's disease

R Schliebs, T Arendt - Journal of neural transmission, 2006 - Springer
Acetylcholine is widely distributed in the nervous system and has been implicated to play a
critical role in cerebral cortical development, cortical activity, controlling cerebral blood flow …