Carcinogenesis is a multistep process triggered by genetic alterations that activate different
signal transduction pathways and cause the progressive transformation of a normal cell into …

In this study, we describe the medicinal plants that have been reported to be antitumor
agents and that have been used in ethnobotanic research in Brazil to answer the following …

Aims In this study, we have investigated the effects of apigenin-7-glucoside, genkwanin and
naringenin, on mouse melanoma B16F10 cell proliferation. Influence of these natural …

Osteoporosis and Alzheimer's disease are typical types of dementia in seniors, which share
common risk factors. Previous studies have shown that citizens with osteoporosis are more …

Vascular smooth muscle cell (VSMC) proliferation and migration play critical roles in arterial
remodeling. Citropten, a natural organic compound belonging to coumarin and its derivative …

African ethnomedicine is essentially based on the traditional use of vegetal extracts. Since
these natural drugs have shown health giving properties, in the present study we increased …

Abstract Chrysin (5, 7-dihydroxyflavone) is a natural and biologically active compound
extracted from honey, plants and propolis. It possesses anti-inflammatory activity, anti …

Vincristine is the drug of choice for Hodgkin's lymphoma, acute lymphoblastic leukemia, and
non-Hodgkin lymphoma. Despite its significant anticancer effects, it causes dose-dependent …

Tumor differentiation is a therapeutic strategy aimed at reactivating the endogenous
differentiation program of cancer cells and inducing cancer cells to mature and differentiate …

Citropten is a coumarin that is mainly found in fruits of Rutaceae trees, but its anti-
inflammatory activities in colitis is still unknown. In this study, we investigated its attenuating …