A review on the modern synthetic approach of benzimidazole candidate

M Faheem, A Rathaur, A Pandey… - …, 2020 - Wiley Online Library
Benzimidazole structure contains imidazole ring fused with phenyl ring at 4‐and 5‐position.
The mono and disubstituted derivatives of benzimidazole are very interesting heterocyclic …

Synthesis, reactivity and biological activity of benzimidazoles

M Alamgir, DSC Black, N Kumar - Bioactive heterocycles III, 2007 - Springer
Benzimidazole is a biologically important scaffold which displays important biological
activities. Recent progress in the synthesis and bioactivity of benzimidazoles is reviewed …

Synthesis, in vitro α-amylase activity, and molecular docking study of new benzimidazole derivatives

H Ullah, H Ullah, M Taha, F Khan, F Rahim… - Russian Journal of …, 2021 - Springer
New benzimidazole derivatives were synthesized by reacting substituted phenacyl bromides
with 1 H-benzimidazole-2-thiols. The synthesized compounds were characterized through 1 …

Synthesis, in vitro α-glucosidase, α-amylase inhibitory potentials and molecular docking study of benzimidazole bearing sulfonamide analogues

H Ullah, T Batool, A Nawaz, F Rahim, F Khan… - Chemical Data …, 2023 - Elsevier
We synthesized fourteen benzimidazole-containing sulfonamide analogs (1–14),
characterized them using methods including NMR and HR-EIMS. The synthesized analogs …

Anticancer, antimicrobial and antiparasitical activities of copper(I) complexes based on N-heterocyclic carbene (NHC) ligands bearing aryl substituents

N Touj, ISA Nasr, WS Koko, TA Khan… - Journal of …, 2020 - Taylor & Francis
New benzimidazolium salts were synthesized as N-heterocyclic carbene precursors. These
NHC precursors were metallated with Cu2O and CuI in acetone and water under reflux to …

Antimicrobial potential of 1H-benzo[d]imidazole scaffold: a review

S Tahlan, S Kumar, B Narasimhan - BMC chemistry, 2019 - Springer
Background Benzimidazole is a heterocyclic moiety whose derivatives are present in many
of the bioactive compounds and posses diverse biological and clinical applications …

2-(2′-Pyridyl) benzimidazole derivatives and their urease inhibitory activity

ZS Saify, A Kamil, S Akhtar, M Taha, A Khan… - Medicinal Chemistry …, 2014 - Springer
Abstract Pyridyl-benzimidazole analogues 1–11 with variable substituent on phenyl ring of
phenacyl moiety were synthesized and evaluated for their urease inhibitory activity. The …

[HTML][HTML] Salinity Stress Responses and Adaptation Mechanisms of Zygophyllum propinquum: A Comprehensive Study on Growth, Water Relations, Ion Balance …

B Gul, S Manzoor, A Rasheed, A Hameed, MZ Ahmed… - Plants, 2024 - mdpi.com
Zygophyllum propinquum (Decne.) is a leaf succulent C4 perennial found in arid saline
areas of southern Pakistan and neighboring countries, where it is utilized as herbal …

6-Nitrobenzimidazole derivatives: Potential phosphodiesterase inhibitors: Synthesis and structure–activity relationship

KM Khan, Z Shah, VU Ahmad, N Ambreen… - Bioorganic & medicinal …, 2012 - Elsevier
6-Nitrobenzimidazole derivatives (1–30) synthesized and their phosphodiesterase inhibitory
activities determined. Out of thirty tested compounds, ten showed a varying degrees of …

Synthesis, crystal structures and biological activities of palladium (II) complexes of benzimidazole and 2-methylbenzimidazole

H Sadaf, M Fettouhi, A Fazal, S Ahmad, BA Farooqi… - Polyhedron, 2019 - Elsevier
Abstract Five palladium (II) complexes (1–5) with benzimidazole and 2-methylbenzimidazole
were prepared and characterized by thermal analysis and, IR and NMR spectroscopy. The …