Alternative pre-mRNA splicing is a tightly controlled process conducted by the spliceosome,
with the assistance of several regulators, resulting in the expression of different transcript …

Alternative pre-mRNA splicing plays important roles in co-transcriptional and post-
transcriptional regulation of gene expression functioned during many developmental …

METTL3 catalyzes the formation of N 6-methyl-adenosine (m 6 A) which has important roles
in regulating various biological processes. However, the in vivo function of Mettl3 remains …

Post-transcriptional RNA modifications critically regulate various biological processes. N 4-
acetylcytidine (ac4C) is an epi-transcriptome, which is highly conserved in all species …

Coordinated regulation of alternative pre-mRNA splicing is essential for germ cell
development. However, the underlying molecular mechanism that controls alternative …

Mammalian spermatogenesis is sustained by mitotic germ cells with self-renewal potential
known as undifferentiated spermatogonia. Maintenance of undifferentiated spermatogonia …

Alternative splicing (AS) is tightly regulated during cell differentiation and development. AS
events are prevalent in the testis, but the splicing regulation in spermatogenesis remains …

Alzheimer's disease (AD) is the most frequent neurodegenerative disorder in the elderly,
occurring in approximately 20% of people older than 80. The molecular causes of AD are …

Background RNA splicing plays significant roles in fundamental biological activities.
However, our knowledge about the roles of alternative splicing and underlying mechanisms …

Infertility is rarely life threatening, however, it poses a serious global health issue posing far-
reaching socio-economic impacts affecting 12–15% of couples worldwide where male factor …