The role of dopamine in NLRP3 inflammasome inhibition: Implications for neurodegenerative diseases
Abstract In the Central Nervous System (CNS), neuroinflammation orchestrated by microglia
and astrocytes is an innate immune response to counteract stressful and dangerous insults …
and astrocytes is an innate immune response to counteract stressful and dangerous insults …
Cellular mechanisms of melatonin: insight from neurodegenerative diseases
D Chen, T Zhang, TH Lee - Biomolecules, 2020 - mdpi.com
Neurodegenerative diseases are the second most common cause of death and
characterized by progressive impairments in movement or mental functioning in the central …
characterized by progressive impairments in movement or mental functioning in the central …
Upregulation of Ca2+-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice
L La Barbera, A Nobili, E Cauzzi, I Paoletti… - Molecular …, 2022 - Springer
Background Recent clinical and experimental studies have highlighted the involvement of
Ventral Tegmental Area (VTA) dopamine (DA) neurons for the early pathogenesis of …
Ventral Tegmental Area (VTA) dopamine (DA) neurons for the early pathogenesis of …
[HTML][HTML] Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer's Disease
What happens precociously to the brain destined to develop Alzheimer's Disease (AD) still
remains to be elucidated and this is one reason why effective AD treatments are missing …
remains to be elucidated and this is one reason why effective AD treatments are missing …
Dopamine neuron degeneration in the Ventral Tegmental Area causes hippocampal hyperexcitability in experimental Alzheimer's Disease
E Spoleti, L La Barbera, E Cauzzi, ML De Paolis… - Molecular …, 2024 - nature.com
Early and progressive dysfunctions of the dopaminergic system from the Ventral Tegmental
Area (VTA) have been described in Alzheimer's Disease (AD). During the long pre …
Area (VTA) have been described in Alzheimer's Disease (AD). During the long pre …
Molecular mechanisms of melatonin-mediated cell protection and signaling in health and disease
DM Kopustinskiene, J Bernatoniene - Pharmaceutics, 2021 - mdpi.com
Melatonin, an endogenously synthesized indolamine, is a powerful antioxidant exerting
beneficial action in many pathological conditions. Melatonin protects from oxidative stress in …
beneficial action in many pathological conditions. Melatonin protects from oxidative stress in …
[HTML][HTML] Behavioral and psychological symptoms in dementia
N Cloak, Y Al Khalili - 2019 - europepmc.org
Behavioral and Psychological Symptoms in Dementia - Abstract - Europe PMC Sign in | Create
an account https://orcid.org Europe PMC Menu About Tools Developers Help Contact us …
an account https://orcid.org Europe PMC Menu About Tools Developers Help Contact us …
Functionalization strategies of polymeric nanoparticles for drug delivery in Alzheimer's disease: Current trends and future perspectives
Alzheimer's disease (AD), the most common form of dementia, is a progressive and
multifactorial neurodegenerative disorder whose primary causes are mostly unknown. Due …
multifactorial neurodegenerative disorder whose primary causes are mostly unknown. Due …
Unifying hypothesis of dopamine neuron loss in neurodegenerative diseases: focusing on Alzheimer's disease
The term “dementia” describes a syndrome caused by several illnesses in which there is
progressive decline in multiple areas of brain function. The main form of dementia is …
progressive decline in multiple areas of brain function. The main form of dementia is …
[HTML][HTML] In vivo mapping of brainstem nuclei functional connectivity disruption in Alzheimer's disease
L Serra, M D'Amelio, C Di Domenico, O Dipasquale… - Neurobiology of …, 2018 - Elsevier
We assessed here functional connectivity changes in the locus coeruleus (LC) and ventral
tegmental area (VTA) of patients with Alzheimer's disease (AD). We recruited 169 patients …
tegmental area (VTA) of patients with Alzheimer's disease (AD). We recruited 169 patients …