Artificial intelligence aids in development of nanomedicines for cancer management
P Tan, X Chen, H Zhang, Q Wei, K Luo - Seminars in cancer biology, 2023 - Elsevier
Over the last decade, the nanomedicine has experienced unprecedented development in
diagnosis and management of diseases. A number of nanomedicines have been approved …
diagnosis and management of diseases. A number of nanomedicines have been approved …
New opportunities and old challenges in the clinical translation of nanotheranostics
Nanoparticle-based systems imbued with both diagnostic and therapeutic functions, known
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …
Engineering radiosensitizer‐based metal‐phenolic networks potentiate STING pathway activation for advanced radiotherapy
Radiotherapy, a mainstay of first‐line cancer treatment, suffers from its high‐dose radiation‐
induced systemic toxicity and radioresistance caused by the immunosuppressive tumor …
induced systemic toxicity and radioresistance caused by the immunosuppressive tumor …
Strategies to improve the EPR effect: A mechanistic perspective and clinical translation
Many efforts have been made to achieve targeted delivery of anticancer drugs to enhance
their efficacy and to reduce their adverse effects. These efforts include the development of …
their efficacy and to reduce their adverse effects. These efforts include the development of …
Nanomedicine for brain cancer
CNS tumors remain among the deadliest forms of cancer, resisting conventional and new
treatment approaches, with mortality rates staying practically unchanged over the past 30 …
treatment approaches, with mortality rates staying practically unchanged over the past 30 …
Surface engineering of lanthanide nanoparticles for oncotherapy
Conspectus Surface-modified lanthanide nanoparticles have been widely developed as an
emerging class of therapeutics for cancer treatment because they exhibit several unique …
emerging class of therapeutics for cancer treatment because they exhibit several unique …
Transforming nuclear medicine with nanoradiopharmaceuticals
I Roy, S Krishnan, AV Kabashin, IN Zavestovskaya… - ACS …, 2022 - ACS Publications
Nuclear medicine is expected to make major advances in cancer diagnosis and therapy;
tumor-targeted radiopharmaceuticals preferentially eradicate tumors while causing minimal …
tumor-targeted radiopharmaceuticals preferentially eradicate tumors while causing minimal …
Radiation‐induced immunogenic cell death for cancer radioimmunotherapy
In cancer treatment, traditional radiotherapy (RT) is routinely conducted in local tumors and
limited by radioresistance, while recently emerged immunotherapy is confronted with low …
limited by radioresistance, while recently emerged immunotherapy is confronted with low …
Anticancer nanotherapeutics in clinical trials: The work behind clinical translation of nanomedicine
A Parodi, EP Kolesova, MV Voronina… - International Journal of …, 2022 - mdpi.com
The ultimate goal of nanomedicine has always been the generation of translational
technologies that can ameliorate current therapies. Cancer disease represented the primary …
technologies that can ameliorate current therapies. Cancer disease represented the primary …
Prospects of nanoparticle-based radioenhancement for radiotherapy
LRH Gerken, ME Gerdes, M Pruschy… - Materials horizons, 2023 - pubs.rsc.org
Radiotherapy is a key pillar of solid cancer treatment. Despite high level of conformal dose
deposition, radiotherapy is limited due to co-irradiation of organs-at risk and subsequent …
deposition, radiotherapy is limited due to co-irradiation of organs-at risk and subsequent …