Maintaining a constant core body temperature of 378C is essential for survival, through
maintaining optimal organ, tissue and cellular function. Tight temperature regulation is …

Even if trauma patients initially avoid death after trauma (due to massive blood volume loss,
primary severe brain injury), they are still at risk for multiple organ failure. Thus, it is crucial to …

Background: To evaluate the feasibility of aortic balloon catheter occlusion in intra-
abdominal hemorrhage. Methods: Effects of transfemoral diaphragmatic aortic balloon …

Background: Reduced metabolic activity improves outcome in many clinical and
experimental models of injury and diseases that result in insufficient blood supply. Recently …

The induction of hypothermia for cellular protection is well established in several clinical
settings. Its role in trauma patients, however, is controversial. This review discusses the …

Several laboratory studies suggested that induced hypothermia during hemorrhagic shock
improves survival. Inhaled hydrogen sulfide (H 2 S) induced hypothermia and decreased …

The majority of injury combinations in multiply injured patients entail the chest, abdomen,
and extremities. Numerous pig models focus on the investigation of posttraumatic …

Objective: Hemorrhagic shock–induced tissue hypoxia induces hyperinflammation,
ultimately causing multiple organ failure. Hyperoxia and hypothermia can attenuate tissue …

Background—Induction of profound hypothermia for emergency preservation and
resuscitation (EPR) of trauma victims who experience exsanguination cardiac arrest may …

The dichotomy between laboratory findings that show a benefit of hypothermia and clinical
findings that suggest detrimental effects remains difficult to explain. For now, preventing …