Sustained hepatic inflammation is an important factor in progression of chronic liver
diseases, including hepatitis C or non-alcoholic steatohepatitis. Liver inflammation is …

Alcoholic liver disease (ALD) refers to the damages to the liver and its functions due to
alcohol overconsumption. It consists of fatty liver/steatosis, alcoholic hepatitis …

Liver disease encompasses a wide variety of liver conditions, including liver failure, liver
cirrhosis and a spectrum of acute and chronic hepatitis, such as alcoholic, fatty, drug, viral …

Adipose tissue represents a large volume of biologically active tissue that exerts substantial
systemic effects in health and disease. Alcohol consumption can profoundly disturb the …

Inflammation is a major contributor to the pathogenesis of almost all liver diseases. Low-
molecular-weight proteins called chemokines are the main drivers of liver infiltration by …

The innate immune system represents the first-line response to invading microbes, tissue
damage, or aberrant cell growth. Many of the proteins and cells involved in innate immunity …

Background & Aims Neutrophils are important immune effectors required for sterile and non-
sterile inflammatory responses. However, neutrophils are associated with pathology in drug …

Background Excess alcohol (ethanol, EtOH) consumption is a significant cause of chronic
liver disease, accounting for nearly half of the cirrhosis‐associated deaths in the United …

Accumulating clinical and experimental evidences have demonstrated that both innate and
adaptive immunity are involved in the pathogenesis of alcoholic liver disease (ALD), in …

Neutrophils are the most abundant type of leukocytes with diverse functions in immune
defense including production of reactive oxygen species, bacteriocidal proteins, neutrophil …