Cost-effectiveness of non-invasive methods for assessment and monitoring of liver fibrosis and cirrhosis in patients with chronic liver disease: systematic review and …

C Crossan, EA Tsochatzis, L Longworth, K Gurusamy… - 2015 - bura.brunel.ac.uk
BACKGROUND: Liver biopsy is the reference standard for diagnosing the extent of fibrosis
in chronic liver disease; however, it is invasive, with the potential for serious complications …

Therapy for hepatitis C virus–related cryoglobulinemic vasculitis

F Dammacco, D Sansonno - New England Journal of Medicine, 2013 - Mass Medical Soc
Cryoglobulins are present in about a quarter of patients with hepatitis C; in some,
cryoglobulinemia can become symptomatic or even life-threatening. This review …

Assessment of pharmacokinetic interactions of the HCV NS5A replication complex inhibitor daclatasvir with antiretroviral agents: ritonavir-boosted atazanavir …

M Bifano, C Hwang, B Oosterhuis, J Hartstra… - Antiviral …, 2013 - journals.sagepub.com
Background Approximately one-third of all HIV-infected individuals are coinfected with HCV,
many of whom will receive concomitant treatment for both infections. With the advent of …

[HTML][HTML] Management of patients with hepatitis B in special populations

E Cholongitas, K Tziomalos, C Pipili - World Journal of …, 2015 - ncbi.nlm.nih.gov
The development of effective nucleos (t) ide analogs (NAs) against hepatitis B virus (HBV)
has improved the outcome of patients with chronic hepatitis B (CHB). This review updates …

Should we await IFN-free regimens to treat HCV genotype 1 treatment-naive patients? A cost-effectiveness analysis (ANRS 95141)

S Deuffic-Burban, M Schwarzinger, D Obach… - Journal of …, 2014 - Elsevier
Background & Aims In treatment-naive patients mono-infected with genotype 1 chronic HCV,
treatments with telaprevir/boceprevir (TVR/BOC)-based triple therapy are standard-of-care …

Safety of direct antiviral agents in the management of hepatitis C

M El Kassas, T Elbaz, E Hafez… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Hepatitis C virus is a hepatotropic virus that generally leads to chronic hepatitis
and various harmful sequelae. The lone standard of treatment has been pegylated interferon …

Drug interactions between antiretrovirals and new or emerging direct-acting antivirals in HIV/hepatitis C virus coinfection

DE Karageorgopoulos, O El-Sherif… - Current opinion in …, 2014 - journals.lww.com
The drug–drug interaction studies for HCV direct-acting antivirals and antiretrovirals are
important in determining the appropriate drug combinations and dosages. The clinical …

Quality indicators as a tool in improving the introduction of new medicines

SM Campbell, B Godman, E Diogene… - Basic & clinical …, 2015 - Wiley Online Library
Quality indicators are increasingly used as a tool to achieve safe and quality clinical care,
cost‐effective therapy, for professional learning, remuneration, accreditation and financial …

Direct‐Acting Antivirals for the Treatment of Chronic Hepatitis C: Open Issues and Future Perspectives

HB Chae, SM Park, SJ Youn - The Scientific World Journal, 2013 - Wiley Online Library
Currently, two direct‐acting antivirals (DAAs) show well‐established efficacy against
hepatitis C virus (HCV), namely, first‐wave protease inhibitors telaprevir and boceprevir …

Peg-interferon plus ribavirin with or without boceprevir or telaprevir for HCV genotype 1: a meta-analysis on the role of response predictors

N Coppola, M Pisaturo, C Sagnelli, E Sagnelli… - PLoS …, 2014 - journals.plos.org
Background & aim To compare the efficacy of pegylated-interferon (Peg-IFN) α-2a or α-2b
and ribavirin given as dual therapy versus triple therapy (Peg-IFN and ribavirin plus …