Molecular ultrasound imaging: current status and future directions
N Deshpande, A Needles, JK Willmann - Clinical radiology, 2010 - Elsevier
Targeted contrast-enhanced ultrasound (molecular ultrasound) is an emerging imaging
strategy that combines ultrasound technology with novel molecularly-targeted ultrasound …
strategy that combines ultrasound technology with novel molecularly-targeted ultrasound …
Response of contrast agents to ultrasound
V Sboros - Advanced drug delivery reviews, 2008 - Elsevier
Microbubbles are used as ultrasonic contrast agents that enhance the ultrasound signals of
the vascular bed. The recent development of site-targeted microbubbles opened up the …
the vascular bed. The recent development of site-targeted microbubbles opened up the …
Attenuation and size distribution measurements of Definity™ and manipulated Definity™ populations
The contrast agent Definity™ has recently been shown to have substantial nonlinear activity
at high ultrasound frequencies (> 10 MHz). In this study, measurements were performed to …
at high ultrasound frequencies (> 10 MHz). In this study, measurements were performed to …
Tumor radiation response enhancement by acoustical stimulation of the vasculature
GJ Czarnota, R Karshafian, PN Burns… - Proceedings of the …, 2012 - National Acad Sciences
We have discovered that ultrasound-mediated microbubble vascular disruption can
enhance tumor responses to radiation in vivo. We demonstrate this effect using a human …
enhance tumor responses to radiation in vivo. We demonstrate this effect using a human …
Classification of the major nonlinear regimes of oscillations, oscillation properties, and mechanisms of wave energy dissipation in the nonlinear oscillations of coated …
Acoustic waves are dissipated when they pass through bubbly media. Dissipation by
bubbles takes place through thermal damping (Td), radiation damping (Rd), and damping …
bubbles takes place through thermal damping (Td), radiation damping (Rd), and damping …
Nonlinear contrast imaging with an array-based micro-ultrasound system
The main goal of this study was to determine the optimal strategy for a real-time nonlinear
contrast mode for small-animal imaging at high frequencies, on a new array-based micro …
contrast mode for small-animal imaging at high frequencies, on a new array-based micro …
[HTML][HTML] Collective nonlinear behavior of interacting polydisperse microbubble clusters
Acoustically excited microbubbles (MBs) have shown to exhibit rich dynamics, enabling
them to be employed in various applications ranging from chemistry to medicine. Exploiting …
them to be employed in various applications ranging from chemistry to medicine. Exploiting …
Subharmonic contrast intravascular ultrasound for vasa vasorum imaging
DE Goertz, ME Frijlink, D Tempel… - Ultrasound in medicine …, 2007 - Elsevier
The feasibility of subharmonic contrast intravascular ultrasound (IVUS) imaging was
investigated using a prototype nonlinear IVUS system and the commercial contrast agent …
investigated using a prototype nonlinear IVUS system and the commercial contrast agent …
Dual-frequency piezoelectric transducers for contrast enhanced ultrasound imaging
For many years, ultrasound has provided clinicians with an affordable and effective imaging
tool for applications ranging from cardiology to obstetrics. Development of microbubble …
tool for applications ranging from cardiology to obstetrics. Development of microbubble …
Microultrasound molecular imaging of vascular endothelial growth factor receptor 2 in a mouse model of tumor angiogenesis
JJ Rychak, J Graba, AMY Cheung… - Molecular …, 2007 - journals.sagepub.com
High-frequency microultrasound imaging of tumor progression in mice enables noninvasive
anatomic and functional imaging at excellent spatial and temporal resolution, although …
anatomic and functional imaging at excellent spatial and temporal resolution, although …