Molecular ultrasound imaging: current status and future directions

N Deshpande, A Needles, JK Willmann - Clinical radiology, 2010 - Elsevier
Targeted contrast-enhanced ultrasound (molecular ultrasound) is an emerging imaging
strategy that combines ultrasound technology with novel molecularly-targeted ultrasound …

Response of contrast agents to ultrasound

V Sboros - Advanced drug delivery reviews, 2008 - Elsevier
Microbubbles are used as ultrasonic contrast agents that enhance the ultrasound signals of
the vascular bed. The recent development of site-targeted microbubbles opened up the …

Attenuation and size distribution measurements of Definity™ and manipulated Definity™ populations

DE Goertz, N de Jong, AFW van der Steen - Ultrasound in medicine & …, 2007 - Elsevier
The contrast agent Definity™ has recently been shown to have substantial nonlinear activity
at high ultrasound frequencies (> 10 MHz). In this study, measurements were performed to …

Tumor radiation response enhancement by acoustical stimulation of the vasculature

GJ Czarnota, R Karshafian, PN Burns… - Proceedings of the …, 2012 - National Acad Sciences
We have discovered that ultrasound-mediated microbubble vascular disruption can
enhance tumor responses to radiation in vivo. We demonstrate this effect using a human …

Classification of the major nonlinear regimes of oscillations, oscillation properties, and mechanisms of wave energy dissipation in the nonlinear oscillations of coated …

AJ Sojahrood, H Haghi, R Karshafian, MC Kolios - Physics of Fluids, 2021 - pubs.aip.org
Acoustic waves are dissipated when they pass through bubbly media. Dissipation by
bubbles takes place through thermal damping (Td), radiation damping (Rd), and damping …

Nonlinear contrast imaging with an array-based micro-ultrasound system

A Needles, M Arditi, NG Rognin, J Mehi… - Ultrasound in medicine …, 2010 - Elsevier
The main goal of this study was to determine the optimal strategy for a real-time nonlinear
contrast mode for small-animal imaging at high frequencies, on a new array-based micro …

[HTML][HTML] Collective nonlinear behavior of interacting polydisperse microbubble clusters

H Haghi, AJ Sojahrood, MC Kolios - Ultrasonics sonochemistry, 2019 - Elsevier
Acoustically excited microbubbles (MBs) have shown to exhibit rich dynamics, enabling
them to be employed in various applications ranging from chemistry to medicine. Exploiting …

Subharmonic contrast intravascular ultrasound for vasa vasorum imaging

DE Goertz, ME Frijlink, D Tempel… - Ultrasound in medicine …, 2007 - Elsevier
The feasibility of subharmonic contrast intravascular ultrasound (IVUS) imaging was
investigated using a prototype nonlinear IVUS system and the commercial contrast agent …

Dual-frequency piezoelectric transducers for contrast enhanced ultrasound imaging

KH Martin, BD Lindsey, J Ma, M Lee, S Li, FS Foster… - Sensors, 2014 - mdpi.com
For many years, ultrasound has provided clinicians with an affordable and effective imaging
tool for applications ranging from cardiology to obstetrics. Development of microbubble …

Microultrasound molecular imaging of vascular endothelial growth factor receptor 2 in a mouse model of tumor angiogenesis

JJ Rychak, J Graba, AMY Cheung… - Molecular …, 2007 - journals.sagepub.com
High-frequency microultrasound imaging of tumor progression in mice enables noninvasive
anatomic and functional imaging at excellent spatial and temporal resolution, although …