Flavonoids are a major group of phytoestrogens associated with physiological effects, and
ecological and social impacts. Although the estrogenic activity of flavonoids was reported by …

A comprehensive summary of more than 450 estrogenic chemicals including estrogenic
endocrine disruptors is provided here to understand the complex and profound impact of …

The increasing percentage of obese individuals in the population and its independent
association of increased risk for the development of cancer have heightened the necessity to …

Lung cancer is progressive and fatal malignancy and is one of the main causes of cancer-
related death worldwide. Leptin (LEP) is a cytokine derived from adipocyte that is known to …

Cancers are regarded as one of the main causes of death and result in high health burden
worldwide. The management of cancer include chemotherapy, surgery and radiotherapy …

Silibinin, a natural flavanone, derived from the milk thistle plant (Silybum marianum), was
illustrated for several medicinal uses such as liver-protective, anti-oxidant, anti-cancer, anti …

Background: Silibinin (SB), the main component of Silymarin (SM), is a natural substance
obtained from the seeds of the milk thistle. SM contains up to 70% of SB as two isoforms: A …

Spinal cord injury (SCI) is damage to the spinal cord that leads to sudden loss of motor and
autonomic function and sensory under the level of the injury. The pathophysiological …

Nanoparticle-based targeted drug delivery has the potential for rendering silibinin
specifically at the favorite site using an external magnetic field. Also, it can circumvent the …

Diabetes mellitus is a metabolic and chronic disorder, which is very common all over the
world. Many genetic and nongenetic factors are involved in the development of type 2 …