[HTML][HTML] Anti-inflammatory drugs as anticancer agents

S Zappavigna, AM Cossu, A Grimaldi… - International journal of …, 2020 - mdpi.com
Inflammation is strictly associated with cancer and plays a key role in tumor development
and progression. Several epidemiological studies have demonstrated that inflammation can …

Cytokine‐and chemokine‐induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy

AA Bhat, S Nisar, M Singh, B Ashraf… - Cancer …, 2022 - Wiley Online Library
Colorectal cancer (CRC) is a predominant life‐threatening cancer, with liver and peritoneal
metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor …

[HTML][HTML] Systemic inflammation in colorectal cancer: Underlying factors, effects, and prognostic significance

AE Tuomisto, MJ Mäkinen… - World journal of …, 2019 - ncbi.nlm.nih.gov
Systemic inflammation is a marker of poor prognosis preoperatively present in around 20%-
40% of colorectal cancer patients. The hallmarks of systemic inflammation include an …

[HTML][HTML] Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles

S Qian, O Golubnitschaja, X Zhan - Epma Journal, 2019 - Springer
A strong relationship exists between tumor and inflammation, which is the hot point in cancer
research. Inflammation can promote the occurrence and development of cancer by …

[HTML][HTML] IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human …

W Zhang, Y Liu, Z Yan, H Yang, W Sun… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background We have previously discovered a relationship between the low expression of
protein tyrosine phosphatase, receptor type O (PTPRO) in tumor-infiltrating T cells and …

[HTML][HTML] Biomarkers for detecting colorectal cancer non-invasively: DNA, RNA or proteins?

A Loktionov - World journal of gastrointestinal oncology, 2020 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a global problem affecting millions of people worldwide. This
disease is unique because of its slow progress that makes it preventable and often curable …

[HTML][HTML] Systematic literature review of IL-6 as a biomarker or treatment target in patients with gastric, bile duct, pancreatic and colorectal cancer

N Vainer, C Dehlendorff, JS Johansen - Oncotarget, 2018 - ncbi.nlm.nih.gov
Gastrointestinal cancer (GI) is a major health problem. Patients with gastric, pancreatic,
colorectal, bile duct and gall bladder cancer often have advanced disease at the time of …

[HTML][HTML] Current advances in prognostic and diagnostic biomarkers for solid cancers: Detection techniques and future challenges

M Pal, T Muinao, HPD Boruah, N Mahindroo - Biomedicine & …, 2022 - Elsevier
Solid cancers are one of the leading causes of cancer related deaths, characterized by rapid
growth of tumour, and local and distant metastases. Current advances on multimodality care …

[HTML][HTML] Systematic review of blood diagnostic markers in colorectal cancer

S Nikolaou, S Qiu, F Fiorentino, S Rasheed… - Techniques in …, 2018 - Springer
The purpose of this systematic review was to compare the diagnostic ability of blood markers
for colorectal cancer (CRC). A systematic review of the literature for diagnostic blood …

[HTML][HTML] IL-6 activities in the tumour microenvironment. Part 1

DC Chonov, MMK Ignatova, JR Ananiev… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
The predominant role of IL-6 in cancer is its key promotion of tumour growth. IL-6 binds IL-6
receptor (IL-6R) and the membrane-bound glycoprotein gp130. The complex I-6/IL …