In situ gelling pH-and temperature-sensitive biodegradable block copolymer hydrogels for drug delivery

NK Singh, DS Lee - Journal of Controlled Release, 2014 - Elsevier
Stimuli-sensitive injectable polymeric hydrogels have been extensively investigated during
the past decade as bioactive agent delivery vehicles and for tissue engineering applications …

Injectable polymeric hydrogels for the delivery of therapeutic agents: A review

QV Nguyen, JH Park, DS Lee - European Polymer Journal, 2015 - Elsevier
Since drug delivery systems have become one of the most promising areas of human health
related research, the applications of biomaterials such as hydrogels have been widely …

Biodegradable and injectable hydrogels in biomedical applications

Y Li, HY Yang, DS Lee - Biomacromolecules, 2022 - ACS Publications
Injectable hydrogels are a unique class of hydrogels that are formed upon injection into
living bodies. They possess features of typical hydrogels such as softness, 3D network …

Injectable block copolymer hydrogels: achievements and future challenges for biomedical applications

CT Huynh, MK Nguyen, DS Lee - Macromolecules, 2011 - ACS Publications
In the past two decades, physical polymeric hydrogels have been extensively explored for
biomedical applications, such as drug delivery and tissue engineering. These hydrogels …

Advances in the stimuli‐responsive injectable hydrogel for controlled release of drugs

C Mo, R Luo, Y Chen - Macromolecular Rapid Communications, 2022 - Wiley Online Library
The stimuli‐responsiveness of injectable hydrogel has been drastically developed for the
controlled release of drugs and has achieved encouraging curative effects in a variety of …

A pH, glucose, and dopamine triple-responsive, self-healable adhesive hydrogel formed by phenylborate–catechol complexation

M Shan, C Gong, B Li, G Wu - Polymer Chemistry, 2017 - pubs.rsc.org
An injectable polyethylene glycol (PEG) hydrogel was successfully prepared via borate–
catechol complexation using dopamine functionalized 4-armed PEG (4-arm-PEG-DA) and …

Recent strategies to develop pH-sensitive injectable hydrogels

T Thambi, JM Jung, DS Lee - Biomaterials Science, 2023 - pubs.rsc.org
“Smart” biomaterials that are responsive to pathological abnormalities are an appealing
class of therapeutic platforms for the development of personalized medications. The …

Biodegradable pH-responsive polyacrylic acid derivative hydrogels with tunable swelling behavior for oral delivery of insulin

X Gao, C He, C Xiao, X Zhuang, X Chen - Polymer, 2013 - Elsevier
Novel biodegradable and pH-sensitive hydrogels composed of four types of pH-sensitive
polyacrylic acid derivatives (PAAD) and a biodegradable poly (l-glutamic acid)(PGA) …

Recent trends in pH/thermo-responsive self-assembling hydrogels: from polyions to peptide-based polymeric gelators

C Chassenieux, C Tsitsilianis - Soft Matter, 2016 - pubs.rsc.org
In this article, we highlight some recent developments in “smart” physical hydrogels
achieved by self-assembling of block type macromolecules. More precisely we focus on two …

Progress on Preparation of pH/Temperature‐Sensitive Intelligent Hydrogels and Applications in Target Transport and Controlled Release of Drugs

L Li, Y He, X Zheng, L Yi, W Nian - International Journal of …, 2021 - Wiley Online Library
Hydrogels with three‐dimensional network structure, hydrophilic, and insoluble in water
which are ideal carrier materials for intelligent drug delivery systems. Intelligent hydrogel …