Past, present and future role of retinal imaging in neurodegenerative disease

AH Kashani, S Asanad, JW Chan, MB Singer… - Progress in retinal and …, 2021 - Elsevier
Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …

Optical coherence tomography angiography in neurodegenerative diseases: a review

G Tsokolas, KT Tsaousis, VF Diakonis, A Matsou… - Eye and …, 2020 - Taylor & Francis
Background Optical coherence tomography angiography (OCT-A) has emerged as a novel,
fast, safe and non-invasive imaging technique of analyzing the retinal and choroidal …

Chromosome 10q26–driven age-related macular degeneration is associated with reduced levels of HTRA1 in human retinal pigment epithelium

BL Williams, NA Seager, JD Gardiner… - Proceedings of the …, 2021 - National Acad Sciences
Genome-wide association studies have identified the chromosome 10q26 (Chr10) locus,
which contains the age-related maculopathy susceptibility 2 (ARMS2) and high temperature …

Retinal biomarkers of cerebral small vessel disease: a systematic review

E Biffi, Z Turple, J Chung, A Biffi - PLoS One, 2022 - journals.plos.org
Introduction Cerebral Small Vessel Disease (CSVD), a progressive degenerative disorder of
small caliber cerebral vessels, represents a major contributor to stroke and vascular …

OCT-Angiography reveals reduced vessel density in the deep retinal plexus of CADASIL patients

P Nelis, I Kleffner, MC Burg, CR Clemens… - Scientific reports, 2018 - nature.com
Optical coherence tomography angiography (OCT-A) represents the most recent tool in
ophthalmic imaging. It allows for a non-invasive, depth-selective and quantitative …

The value of optical coherence tomography angiography (OCT-A) in neurological diseases

AJ Augustin, J Atorf - Diagnostics, 2022 - mdpi.com
Optical coherence tomography angiography (OCT-A) was commercially introduced in 2014.
OCT-A allows a fast, non-invasive, three-dimensional analysis of the retinal vasculature from …

Novel uses of retinal imaging with optical coherence tomography in multiple sclerosis

FC Oertel, HG Zimmermann, AU Brandt… - Expert Review of …, 2019 - Taylor & Francis
ABSTRACT Introduction: Multiple Sclerosis (MS) is the most common chronic autoimmune
neuroinflammatory condition in young adults. It is often accompanied by optic neuritis (ON) …

Association of optic disc pallor and RNFL thickness with cerebral small vessel disease in the PREVENT‐Dementia study

S Gibbon, A Low, C Hamid… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION We tested associations between two retinal measures (optic disc pallor,
peripapillary retinal nerve fiber layer [pRNFL] thickness) and four magnetic resonance …

Serum neurofilament light correlates with CADASIL disease severity and survival

G Gravesteijn, JW Rutten, IMW Verberk… - Annals of clinical …, 2019 - Wiley Online Library
Objective To validate whether serum Neurofilament Light‐chain (NfL) levels correlate with
disease severity in CADASIL, and to determine whether serum NfL predicts disease …

Effects of high-intensity interval training on optic nerve head and macular perfusion using optical coherence tomography angiography in healthy adults

B Schmitz, P Nelis, F Rolfes, M Alnawaiseh, A Klose… - Atherosclerosis, 2018 - Elsevier
Background and aims High-intensity interval training (HIIT) has been identified to be efficient
for increasing health-related fitness in general and in lifestyle-induced chronic diseases …