Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Receptor-ligand bonds strengthened by tensile mechanical force are referred to as catch
bonds. This review examines experimental data and biophysical theory to analyze why …

The function of the integrin family of receptors as central mediators of cell-extracellular
matrix (ECM) and cell–cell adhesion requires a remarkable convergence of interactions and …

The Escherichia coli fimbrial adhesive protein, FimH, mediates shear-dependent binding to
mannosylated surfaces via force-enhanced allosteric catch bonds, but the underlying …

Adherent-invasive Escherichia coli (AIEC) are abnormally predominant on Crohn's disease
(CD) ileal mucosa. AIEC reference strain LF82 adheres to ileal enterocytes via the common …

The bacterial adhesive protein, FimH, is the most common adhesin of Escherichia coli and
mediates weak adhesion at low flow but strong adhesion at high flow. There is evidence that …

Catch bonds are bonds between a ligand and its receptor that are enhanced by mechanical
force pulling the ligand-receptor complex apart. To date, catch-bond formation has been …

Urinary catheters are standard medical devices utilized in both hospital and nursing home
settings, but are associated with a high frequency of catheter-associated urinary tract …

Optical biosensor technology continues to be the method of choice for label‐free, real‐time
interaction analysis. But when it comes to improving the quality of the biosensor literature …

Abstract Background Uropathogenic Escherichia coli (UPEC) cause urinary tract infections
(UTIs) in approximately 50% of women. These bacteria use type 1 and P pili for host …