Lipid droplets (also known as lipid bodies) are lipid-rich, cytoplasmic organelles that play
important roles in cell signaling, lipid metabolism, membrane trafficking, and the production …

Cancer cells possess remarkable abilities to adapt to adverse environmental conditions.
Their survival during severe nutrient and oxidative stress depends on their capacity to …

An in vivo model of antiangiogenic therapy allowed us to identify genes upregulated by
bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of …

The Warburg effect describes the phenomenon by which cancer cells obtain energy from
glycolysis even under normoxic (O2-sufficient) conditions. Tumor tissues are generally …

Simple Summary Metabolic reprogramming is gaining attentions as a hallmark of cancers.
However, lipid metabolism has been difficult to analyze due to technical problems. In recent …

Since oxygen is one of the critical limiting factors for maintaining cell viability and function, a
great deal of effort is being focused on improving the oxygen supply to three-dimensional …

When the brain is in a pathological state, the content of lipid droplets (LDs), the lipid storage
organelles, is increased, particularly in glial cells, but rarely in neurons. The biology and …

Purpose: Glioblastoma represents the most common primary brain tumor. Although
antiangiogenics are used in the recurrent setting, they do not prolong survival. Glioblastoma …

Radiotherapy is a widely used treatment option in cancer. However, recent evidence
suggests that doses of ionizing radiation (IR) delivered inside the tumor target volume …

Cells exposed to stress of different origins synthesize triacylglycerols and generate lipid
droplets (LD), but the physiological relevance of this response is uncertain. Using complete …