Cancer is a disease with complex pathological process. Current chemotherapy faces
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …

Polyethylene glycol (PEG) is a versatile polymer that is widely used as an additive in foods
and cosmetics, and as a carrier in PEGylated therapeutics. Even though PEG is thought to …

Doxorubicin or Adriamycin, is one of the most widely used chemotherapeutic drug for
treating a myriad of cancers. It induces cell death through multiple intracellular targets …

Liposomes, which possess the properties of nano-scale, biofilm similar structure, excellent
biocompatibility, become more and more useful in the drug development as the delivery …

In this review we provide an up to date snapshot of nanomedicines either currently approved
by the US FDA, or in the FDA clinical trials process. We define nanomedicines as …

In the past decade, the rapid evolution of nanotechnology has spawned many fascinating
opportunities and advances for disease diagnosis and therapy. The currently available …

Background: Nanotechnology is gaining significant attention worldwide for cancer treatment.
Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a …

PEGylation of lipid-based nanoparticles and other nanocarriers is widely used to increase
their stability and plasma half-life. However, either pre-existing or de novo formed anti-PEG …

ABSTRACT A commonly held view is that nanocarriers conjugated to polyethylene glycol
(PEG) are non-immunogenic. However, many studies have reported that unexpected …

Nanomedicines have evolved into various forms including dendrimers, nanocrystals,
emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles since …