Role of metallic nanoparticles in vaccinology: implications for infectious disease vaccine development

LM Marques Neto, A Kipnis… - Frontiers in …, 2017 - frontiersin.org
Subunit vaccines are safer but less immunogenic than live-attenuated vaccines or whole cell
inactivated vaccines. Adjuvants are used to enhance and modulate antigen (Ag) …

Nanoparticles as adjuvants in vaccine delivery

A Garg, HK Dewangan - Critical Reviews™ in Therapeutic …, 2020 - dl.begellhouse.com
Nanotechnology provides an excellent platform for the development of a new generation of
vaccines. These are based on purified subunit proteins or polysaccharides, recombinant …

[图书][B] Encyclopedia of Polymer Applications, 3 Volume Set

M Mishra - 2018 - taylorfrancis.com
Undoubtedly the applications of polymers are rapidly evolving. Technology is continually
changing and quickly advancing as polymers are needed to solve a variety of day-to-day …

Nano-based approaches in the development of antiviral agents and vaccines

Y Li, Y Xiao, Y Chen, K Huang - Life sciences, 2021 - Elsevier
Outbreaks and the rapid transmission of viruses, such as coronaviruses and influenza
viruses, are serious threats to human health. A major challenge in combating infectious …

Surface-tailored anti-HER2/neu-solid lipid nanoparticles for site-specific targeting MCF-7 and BT-474 breast cancer cells

EB Souto, S Doktorovova, JR Campos… - European Journal of …, 2019 - Elsevier
CAB51, a compact antibody against human epithelial growth receptor 2 (HER2, ErbB2), has
been linked to cationic Solid Lipid Nanoparticles (SLN) via streptavidin-biotin interaction and …

Tailoring nanostructured lipid carriers for the delivery of protein antigens: Physicochemical properties versus immunogenicity studies

T Courant, E Bayon, HL Reynaud-Dougier, C Villiers… - Biomaterials, 2017 - Elsevier
New vaccine formulations are still highly anticipated in the near-future to face incoming
health challenges, such as emergence or reemergence of severe infectious diseases …

Nanoparticle vaccines against viral infections

FB Sulczewski, RB Liszbinski, PRT Romão… - Archives of …, 2018 - Springer
Despite numerous efforts, we still do not have prophylactic vaccines for many clinically
relevant viruses, such as HIV, hepatitis C virus, Zika virus, and respiratory syncytial virus …

Recombinant programmed cell death protein 1 functions as an immune check point blockade and enhances anti-cancer immunity

J Hwang, EK An, W Zhang, HB Park, SJ Kim, D Yadav… - Biomaterials, 2022 - Elsevier
Effective cancer therapy aims to treat not only primary tumors but also metastatic and
recurrent cancer. Immune check point blockade-mediated immunotherapy showed …

Engineered nanoparticle applications for recombinant influenza vaccines

ZR Sia, MS Miller, JF Lovell - Molecular pharmaceutics, 2020 - ACS Publications
Influenza viruses cause seasonal epidemics and represent a pandemic risk. With current
vaccine methods struggling to protect populations against emerging strains, there is a …

Protein nanoparticle-mediated delivery of recombinant influenza hemagglutinin enhances immunogenicity and breadth of the antibody response

AJ Badten, A Ramirez… - ACS Infectious …, 2023 - ACS Publications
The vast majority of seasonal influenza vaccines administered each year are derived from
virus propagated in eggs using technology that has changed little since the 1930s. The …