Abstract BRCA1/2 gene mutations, which result in a dysfunction of homologous
recombination repair, have been discovered in at least 5% of breast cancer (BC) patients …

Objective To investigate the prevalence and spectrum of BRCA1 and BRCA2 mutations in
Chinese Hakka patients with breast and ovarian cancer. Methods A total of 1,664 breast or …

Methods Recent domestic and foreign guidelines, as well as clinical studies related to
refractory mTNBC on PubMed and the China National Knowledge Infrastructure (CNKI) …

Objective: Despite several nationwide cohort studies of germline BRCA1/2 mutations and
several small cohort studies of somatic BRCA1/2 mutations in Chinese epithelial ovarian …

Abstract Background and Objective: Pterygota alata (Roxb.) R. Br. bark extract has been
studied to have cytotoxic activity on 4T1 cells. This study was conducted to determine the …

Purpose The study aimed to compare the survival outcomes and efficacy of platinum in early
breast cancer patients with BRCA1 and BRCA2 mutations. Methods Patients diagnosed with …

Objective: Our aim was to explore the influence of humanistic care based on Carolina care
model on postoperative recovery and quality of life in patients with ovarian cancer (OC) …

Purpose Although the burden of breast cancer remains especially high in rural China, data
on the clinicopathological characteristics and prevalence of the breast cancer susceptibility …

Objective: Hereditary colorectal cancer (CRC) accounts for approximately 5%–10% of all
CRC cases. The full profile of CRC-related germline mutations and the corresponding …

Methods To investigate the mutation characteristics of cancer susceptibility genes in the
Chinese ovarian cancer population and the associations between gene mutations and …