Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine

M Brown, J Li, C Moraes, M Tabrizian, NYK Li-Jessen - Biomaterials, 2022 - Elsevier
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

[HTML][HTML] Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges

W Wei, H Dai - Bioactive materials, 2021 - Elsevier
In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Extracellular matrix-based materials for regenerative medicine

GS Hussey, JL Dziki, SF Badylak - Nature Reviews Materials, 2018 - nature.com
In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …

Injectable hydrogels for cartilage and bone tissue engineering

M Liu, X Zeng, C Ma, H Yi, Z Ali, X Mou, S Li, Y Deng… - Bone research, 2017 - nature.com
Tissue engineering has become a promising strategy for repairing damaged cartilage and
bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels …

Extracellular matrix hydrogels from decellularized tissues: Structure and function

LT Saldin, MC Cramer, SS Velankar, LJ White… - Acta biomaterialia, 2017 - Elsevier
Extracellular matrix (ECM) bioscaffolds prepared from decellularized tissues have been
used to facilitate constructive and functional tissue remodeling in a variety of clinical …

Manufacturing of hydrogel biomaterials with controlled mechanical properties for tissue engineering applications

A Vedadghavami, F Minooei, MH Mohammadi… - Acta biomaterialia, 2017 - Elsevier
Hydrogels have been recognized as crucial biomaterials in the field of tissue engineering,
regenerative medicine, and drug delivery applications due to their specific characteristics …

Advances in injectable self-healing biomedical hydrogels

Y Tu, N Chen, C Li, H Liu, R Zhu, S Chen, Q Xiao, J Liu… - Acta Biomaterialia, 2019 - Elsevier
In recent years, implantable biomaterials have attracted significant interest owing to their
potentials for use in the therapy of physical defects and traumas. Among the implantable …

miR-23a-3p-abundant small extracellular vesicles released from Gelma/nanoclay hydrogel for cartilage regeneration

H Hu, L Dong, Z Bu, Y Shen, J Luo… - Journal of …, 2020 - Taylor & Francis
Articular cartilage has limited self-regenerative capacity and the therapeutic methods for
cartilage defects are still dissatisfactory in clinic. Recent studies showed that exosomes …

Extracellular matrix hydrogel therapies: In vivo applications and development

MT Spang, KL Christman - Acta biomaterialia, 2018 - Elsevier
Decellularized extracellular matrix (ECM) has been widely used for tissue engineering
applications and is becoming increasingly versatile as it can take many forms, including …

Designing decellularized extracellular matrix‐based bioinks for 3D bioprinting

A Abaci, M Guvendiren - Advanced healthcare materials, 2020 - Wiley Online Library
Abstract 3D bioprinting is an emerging technology to fabricate tissues and organs by
precisely positioning cells into 3D structures using printable cell‐laden formulations known …