Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

Glioblastoma (GBM) is the highest-grade form of glioma, as well as one of the most
aggressive types of cancer, exhibiting rapid cellular growth and highly invasive behavior …

Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain
tumor in adults. Current treatment options typically consist of surgery followed by …

Glioblastoma (GBM) is a devastating human malignancy. GBM stem-like cells (GSCs) drive
tumor initiation and progression. Yet the molecular determinants defining GSCs in their …

Macrophages are widely distributed innate immune cells that play indispensable roles in the
innate and adaptive immune response to pathogens and in‐tissue homeostasis …

Glioblastoma is a highly angiogenetic malignancy, the neoformed vessels of which are
thought to arise by sprouting of pre-existing brain capillaries. The recent demonstration that …

The role of autophagy in cancer onset and progression appears still controversial. On one
hand, autophagy allows cancer cell to survive in unfavorable environmental conditions, on …

Inactivation of cancer stem cells (CSCs) is of utmost importance for tumor cure after
radiotherapy. An increasing body of evidence complies with a higher radioresistance of …

The niche concept was originally developed to describe the location of normal neural stem
cells (NSCs) in the subependymal layer of the sub-ventricular zone. In this paper, its …

Brain tumors remain one of the most difficult tumors to treat and, depending on the
diagnosis, have a poor prognosis. Of brain tumors, glioblastoma (GBM) is the most common …