Nitric oxide/nitric oxide synthase system in the pathogenesis of neurodegenerative disorders—an overview
OM Iova, GE Marin, I Lazar, I Stanescu, G Dogaru… - Antioxidants, 2023 - mdpi.com
Nitric oxide, a ubiquitous molecule found throughout the natural world, is a key molecule
implicated in many central and benefic molecular pathways and has a well-established role …
implicated in many central and benefic molecular pathways and has a well-established role …
An overview of NO signaling pathways in aging
AM Pourbagher-Shahri, T Farkhondeh, M Talebi… - Molecules, 2021 - mdpi.com
Nitric Oxide (NO) is a potent signaling molecule involved in the regulation of various cellular
mechanisms and pathways under normal and pathological conditions. NO production, its …
mechanisms and pathways under normal and pathological conditions. NO production, its …
Triterpenoids and meroterpenoids from the edible Ganoderma resinaceum and their potential anti-inflammatory, antioxidant and anti-apoptosis activities
RW Kou, B Xia, ZJ Wang, JN Li, JR Yang, YQ Gao… - Bioorganic …, 2022 - Elsevier
Ganoderma resinaceum, as a traditional edible mushroom, has been widely reported to
improve neurodegenerative diseases characterized by oxidative stress and inflammation. In …
improve neurodegenerative diseases characterized by oxidative stress and inflammation. In …
[HTML][HTML] Role of primary aging hallmarks in Alzheimer´ s disease
J Zhao, J Huai - Theranostics, 2023 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most common neurodegenerative disease, which severely
threatens the health of the elderly and causes significant economic and social burdens. The …
threatens the health of the elderly and causes significant economic and social burdens. The …
[HTML][HTML] In vivo hydrogen peroxide diffusivity in brain tissue supports volume signaling activity
Hydrogen peroxide is a major redox signaling molecule underlying a novel paradigm of cell
function and communication. A role for H 2 O 2 as an intercellular signaling molecule and …
function and communication. A role for H 2 O 2 as an intercellular signaling molecule and …
Neuroprotective Activity of Melittin—The Main Component of Bee Venom—Against Oxidative Stress Induced by Aβ25–35 in In Vitro and In Vivo Models
CD Nguyen, G Lee - Antioxidants, 2021 - mdpi.com
Melittin, a 26-amino acid peptide, is the main component of the venom of four honeybee
species and exhibits neuroprotective actions. However, it is unclear how melittin ameliorates …
species and exhibits neuroprotective actions. However, it is unclear how melittin ameliorates …
Disturbed balance of inhibitory signaling links hearing loss and cognition
Neuronal hyperexcitability in the central auditory pathway linked to reduced inhibitory
activity is associated with numerous forms of hearing loss, including noise damage, age …
activity is associated with numerous forms of hearing loss, including noise damage, age …
Bee Venom Activates the Nrf2/HO-1 and TrkB/CREB/BDNF Pathways in Neuronal Cell Responses against Oxidative Stress Induced by Aβ1–42
CD Nguyen, J Yoo, SY Hwang, SY Cho, M Kim… - International Journal of …, 2022 - mdpi.com
Honeybee venom has recently been considered an anti-neurodegenerative agent, primarily
due to its anti-inflammatory effects. The natural accumulation of amyloid-beta (Aβ) in the …
due to its anti-inflammatory effects. The natural accumulation of amyloid-beta (Aβ) in the …
Carvacrol improved learning and memory and attenuated the brain tissue oxidative damage in aged male rats
MA Forqani, M Akbarian, S Amirahmadi… - International Journal …, 2023 - Taylor & Francis
Introduction: Aging is an unavoidable process in the body that is accompanied by impaired
tissue homeostasis and various changes. Carvacrol has attracted considerable attention for …
tissue homeostasis and various changes. Carvacrol has attracted considerable attention for …
A high fat/cholesterol diet recapitulates some Alzheimer's disease-like features in mice: focus on hippocampal mitochondrial dysfunction
G Mancini, C Dias, CF Lourenco… - Journal of …, 2021 - content.iospress.com
Background: Ample evidence from clinical and pre-clinical studies suggests mid-life
hypercholesterolemia as a risk factor for developing Alzheimer's disease (AD) at a later age …
hypercholesterolemia as a risk factor for developing Alzheimer's disease (AD) at a later age …