Histoplasma Capsulatum: Mechanisms for Pathogenesis

J Mittal, MG Ponce, I Gendlina… - Fungal Physiology and …, 2019 - Springer
Histoplasmosis, caused by the dimorphic environmental fungus Histoplasma capsulatum, is
a major mycosis on the global stage. Acquisition of the fungus by mammalian hosts can be …

Pathogenicity & virulence of Histoplasma capsulatum - A multifaceted organism adapted to intracellular environments

AF Valdez, DZ Miranda, AJ Guimarães, L Nimrichter… - Virulence, 2022 - Taylor & Francis
Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus
Histoplasma capsulatum. Although healthy individuals can develop histoplasmosis, the …

Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans

G Vargas, JDB Rocha, DL Oliveira… - Cellular …, 2015 - Wiley Online Library
The release of extracellular vesicles (EV) by fungal organisms is considered an alternative
transport mechanism to trans‐cell wall passage of macromolecules. Previous studies have …

Chaperonin 60: a paradoxical, evolutionarily conserved protein family with multiple moonlighting functions

B Henderson, MA Fares, PA Lund - Biological Reviews, 2013 - Wiley Online Library
Chaperonin 60 is the prototypic molecular chaperone, an essential protein in eukaryotes
and prokaryotes, whose sequence conservation provides an excellent basis for …

Extracellular vesicle-associated transitory cell wall components and their impact on the interaction of fungi with host cells

L Nimrichter, MM De Souza, M Del Poeta… - Frontiers in …, 2016 - frontiersin.org
Classic cell wall components of fungi comprise the polysaccharides glucans and chitin, in
association with glycoproteins and pigments. During the last decade, however, system …

Surface Architecture of Histoplasma Capsulatum

AJ Guimarães, MD de Cerqueira… - Frontiers in …, 2011 - frontiersin.org
The dimorphic fungal pathogen Histoplasma capsulatum is the most frequent cause of
clinically significant fungal pneumonia in humans. H. capsulatum virulence is achieved, in …

[HTML][HTML] The heat shock protein (Hsp) 70 of Cryptococcus neoformans is associated with the fungal cell surface and influences the interaction between yeast and host …

CP Silveira, AC Piffer, L Kmetzsch, FL Fonseca… - Fungal Genetics and …, 2013 - Elsevier
The pathogenic yeast Cryptococcus neoformans secretes numerous proteins, such as heat
shock proteins, by unconventional mechanisms during its interaction with host cells. Hsp70 …

Design of a Multi-Epitope Vaccine against Histoplasma capsulatum through Immunoinformatics Approaches

PH Marques, S Tiwari, AG Felice, AK Jaiswal… - Journal of Fungi, 2024 - mdpi.com
Histoplasmosis is a widespread systemic disease caused by Histoplasma capsulatum,
prevalent in the Americas. Despite its significant morbidity and mortality rates, no vaccines …

Histoplasma Virulence and Host Responses

MR Mihu, JD Nosanchuk - International journal of microbiology, 2012 - Wiley Online Library
Histoplasma capsulatum is the most prevalent cause of fungal respiratory disease. The
disease extent and outcomes are the result of the complex interaction between the pathogen …

Immunoproteomics Reveals Pathogen's Antigens Involved in Homo sapiensHistoplasma capsulatum Interaction and Specific Linear B-Cell Epitopes in …

MA Almeida, R Almeida-Paes, AJ Guimarães… - Frontiers in Cellular …, 2020 - frontiersin.org
Histoplasmosis is one of the most frequent systemic mycosis in HIV patients. In these
patients, histoplasmosis has high rates of morbidity/mortality if diagnosis and treatment are …