Neuroblastoma is a paediatric cancer of the sympathetic nervous system and the most
common solid tumour of infancy, contributing to 15% of paediatric oncology deaths. Current …

Neuroblastoma is a childhood cancer derived from cells of neural crest origin. The hallmarks
of its enigmatic character include its propensity for spontaneous regression under some …

High-risk neuroblastoma is often distinguished by amplification of MYCN and loss of
differentiation potential. We performed high-throughput drug screening of epigenetic …

Abstract Adult Schwann cells (SCs) possess an inherent plastic potential. This plasticity
allows SCs to acquire repair-specific functions essential for peripheral nerve regeneration …

Peripheral neuroblastic tumors (neuroblastoma, ganglioneuroblastoma and
ganglioneuroma) are heterogeneous and their diverse and wide range of clinical behaviors …

The purpose of this study was to investigate the differential expression and functional roles
of long non-coding RNAs (lncRNAs) in neuroblastoma tissue. LncRNA microarrays were …

Cancerous cells must cooperate with the surrounding stroma and non-malignant cells within
the microenvironment to support the growth and invasion of the tumor. The nervous system …

The International Neuroblastoma Pathology Classification (INPC), which distinguishes a
favorable histology (FH) and an unfavorable histology (UH), is one of the most powerful …

High histone deacetylase (HDAC) 8 and HDAC10 expression levels have been identified as
predictors of exceptionally poor outcomes in neuroblastoma, the most common extracranial …

Simple Summary Neuroblastoma is a pediatric tumor originating from the precursors of
sympathetic nerves. The disease is known for its high heterogeneity. Hence, developing …