High‐performance liquid chromatography‐based assay optimization for the detection of plasma amino acids for applications in metabolic disorders in developing …

M Wasim, HN Khan, A Tawab, F Habib… - Separation …, 2023 - Wiley Online Library
Plasma amino acids are generally analyzed through ion exchange chromatography, a
reproducible but time‐consuming method. Here, we report the optimization of a reverse …

Label free quantitative proteomic profiling of serum samples of intellectually disabled young patients revealed dysregulation of complement coagulation and …

S Vankwani, MR Mirza, FR Awan, M Zafar… - Metabolic Brain …, 2024 - Springer
Intellectual disability is a heterogeneous disorder, diagnosed using intelligence quotient (IQ)
score criteria. Currently, no specific clinical test is available to diagnose the disease and its …

[HTML][HTML] Initiating Newborn Screening for Metabolic Disorders in Pakistan: A Qualitative Study of the Early Challenges and Opportunities

M Wasim, HN Khan, H Ayesha, FR Awan - Rare, 2023 - Elsevier
In multiple countries, newborn screening (NBS) initiatives have provided prevalence insights
for inborn errors of metabolism (IEM), but Pakistan lacks such data. Few reports exist on IEM …