Role of free radical in atherosclerosis, diabetes and dyslipidaemia: larger‐than‐life

R Singh, S Devi, R Gollen - Diabetes/metabolism research and …, 2015 - Wiley Online Library
During the past few decades, there have been numerous studies related to free radical
chemistry. Free radicals including reactive oxygen species (ROS) and reactive nitrogen …

[HTML][HTML] Betulinic acid alleviates spleen oxidative damage induced by acute intraperitoneal exposure to T-2 toxin by activating Nrf2 and inhibiting MAPK signaling …

L Kong, L Zhu, X Yi, Y Huang, H Zhao, Y Chen, Z Yuan… - Antioxidants, 2021 - mdpi.com
T-2 toxin, which is mainly produced by specific strains of Fusarium in nature, can induce
immunotoxicity and oxidative stress, resulting in immune organ dysfunction and apoptosis …

MiR-133a-3p/Sirt1 epigenetic programming mediates hypercholesterolemia susceptibility in female offspring induced by prenatal dexamethasone exposure

X Li, W Hu, L Li, Z Chen, T Jiang, D Zhang, K Liu… - Biochemical …, 2022 - Elsevier
Mounting evidence indicates that adverse intrauterine conditions increase offspring's
hypercholesterolemia susceptibility in adulthood. This study aimed to confirm prenatal …

Phytochemical screening and the effect of Trichosanthes dioica in high‐fat diet induced atherosclerosis in Wistar rats

AK Shrivastava, S Thapa, L Shrestha, RK Mehta… - Food …, 2021 - Wiley Online Library
Trichosanthes dioica fruit pericarp has a powerful hypolipidemic and antioxidant properties.
Wistar rats were divided into five groups (n= 30). The normal control group received vehicle …

Antihyperlipidaemic effect of triterpenic acid-enriched fraction from Cyclocarya paliurus leaves in hyperlipidaemic rats

Z Wu, T Gao, R Zhong, Z Lin, C Jiang… - Pharmaceutical …, 2017 - Taylor & Francis
Abstract Context: Cyclocarya paliurus (Batal) Iljinskaja (Juglandaceae) is an edible and
medicinal plant; the leaves are used in Chinese folkloric medicine to treat dyslipidaemia and …

Antiatherosclerotic effect of an antibody that binds to extracellular matrix glycosaminoglycans

Y Soto, E Acosta, L Delgado, A Pérez… - … , and vascular biology, 2012 - Am Heart Assoc
Objective—Subendothelial retention of proatherogenic lipoproteins by proteoglycans is
critical in atherosclerosis. The aim of this study was to characterize the recognition and …

Ozone oxidative preconditioning prevents atherosclerosis development in New Zealand white rabbits

L Delgado-Roche, G Martínez-Sánchez… - Journal of …, 2013 - journals.lww.com
Atherosclerosis is a major cause of death in the Western World. It is known that Lipofundin
20% induces atherosclerotic lesions, whereas ozone at low doses has been satisfactorily …

[HTML][HTML] Ozone-oxidative preconditioning prevents doxorubicin-induced cardiotoxicity in Sprague-Dawley Rats

L Delgado-Roche, Y Hernández-Matos… - Sultan Qaboos …, 2014 - ncbi.nlm.nih.gov
Objectives: Induced dilated cardiomyopathy is the main limitation of the anti-cancer drug
doxorubicin, which causes oxidative stress and cardiomyocyte death. As ozone therapy can …

Prenatal caffeine exposure induced high susceptibility to metabolic syndrome in adult female offspring rats and its underlying mechanisms

L Pei, C Yuan, Y Guo, H Kou, L Xia, L Zhang… - Reproductive …, 2017 - Elsevier
Our previous studies have demonstrated that prenatal caffeine exposure (PCE) induced an
intrauterine programming of hypothalamic–pituitary–adrenal axis (HPAA)-associated …

The treatment with an anti-glycosaminoglycan antibody reduces aortic oxidative stress in a rabbit model of atherosclerosis

L Delgado-Roche, E Acosta, Y Soto… - Free Radical …, 2013 - Taylor & Francis
Retained low-density lipoproteins (LDL) by arterial glycosaminoglycans (GAG) are more
susceptible to reactive oxygen species-mediated oxidation, contributing to oxidative stress …