The complex relationship between virulence and antibiotic resistance
Antibiotic resistance, prompted by the overuse of antimicrobial agents, may arise from a
variety of mechanisms, particularly horizontal gene transfer of virulence and antibiotic …
variety of mechanisms, particularly horizontal gene transfer of virulence and antibiotic …
Mechanisms of DNA uptake by naturally competent bacteria
D Dubnau, M Blokesch - Annual review of genetics, 2019 - annualreviews.org
Transformation is a widespread mechanism of horizontal gene transfer in bacteria. DNA
uptake to the periplasmic compartment requires a DNA-uptake pilus and the DNA-binding …
uptake to the periplasmic compartment requires a DNA-uptake pilus and the DNA-binding …
Quorum Sensing Regulation of Competence and Bacteriocins in Streptococcus pneumoniae and mutans
E Shanker, MJ Federle - Genes, 2017 - mdpi.com
The human pathogens Streptococcus pneumoniae and Streptococcus mutans have both
evolved complex quorum sensing (QS) systems that regulate the production of bacteriocins …
evolved complex quorum sensing (QS) systems that regulate the production of bacteriocins …
Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39
J Slager, R Aprianto, JW Veening - Nucleic acids research, 2018 - academic.oup.com
A precise understanding of the genomic organization into transcriptional units and their
regulation is essential for our comprehension of opportunistic human pathogens and how …
regulation is essential for our comprehension of opportunistic human pathogens and how …
Quorum sensing integrates environmental cues, cell density and cell history to control bacterial competence
S Moreno-Gámez, RA Sorg, A Domenech… - Nature …, 2017 - nature.com
Streptococcus pneumoniae becomes competent for genetic transformation when exposed to
an autoinducer peptide known as competence-stimulating peptide (CSP). This peptide was …
an autoinducer peptide known as competence-stimulating peptide (CSP). This peptide was …
Interbacterial predation as a strategy for DNA acquisition in naturally competent bacteria
JW Veening, M Blokesch - Nature Reviews Microbiology, 2017 - nature.com
Natural competence enables bacteria to take up exogenous DNA. The evolutionary function
of natural competence remains controversial, as imported DNA can act as a source of …
of natural competence remains controversial, as imported DNA can act as a source of …
Bacteriocins: not only antibacterial agents
This commentary was aimed at shedding light on the multifunction of bacteriocins mainly
those produced by lactic acid bacteria. These antibacterial agents were first used to improve …
those produced by lactic acid bacteria. These antibacterial agents were first used to improve …
High-resolution analysis of the pneumococcal transcriptome under a wide range of infection-relevant conditions
R Aprianto, J Slager, S Holsappel… - Nucleic acids …, 2018 - academic.oup.com
Streptococcus pneumoniae is an opportunistic human pathogen that typically colonizes the
nasopharyngeal passage and causes lethal disease in other host niches, such as the lung …
nasopharyngeal passage and causes lethal disease in other host niches, such as the lung …
Ribosomally synthesized peptides, foreground players in microbial interactions: recent developments and unanswered questions
S Rebuffat - Natural Product Reports, 2022 - pubs.rsc.org
It is currently well established that multicellular organisms live in tight association with
complex communities of microorganisms including a large number of bacteria. These are …
complex communities of microorganisms including a large number of bacteria. These are …
Streptococcus pneumoniae two-component regulatory systems: The interplay of the pneumococcus with its environment
A Gómez-Mejia, G Gámez, S Hammerschmidt - International Journal of …, 2018 - Elsevier
Streptococcus pneumoniae is a human pathobiont possessing a diverse array of
multifunctional proteins essential for bacterial fitness and virulence. Gene expression is …
multifunctional proteins essential for bacterial fitness and virulence. Gene expression is …