Mesenchymal stem cells for spinal cord injury: current options, limitations, and future of cell therapy
Spinal cord injury (SCI) constitutes an inestimable public health issue. The most crucial
phase in the pathophysiological process of SCI concerns the well-known secondary injury …
phase in the pathophysiological process of SCI concerns the well-known secondary injury …
Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem
JM Griffin, F Bradke - EMBO molecular medicine, 2020 - embopress.org
The recent years saw the advent of promising preclinical strategies that combat the
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …
Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis
D Karussis, C Karageorgiou… - Archives of …, 2010 - jamanetwork.com
Objective To evaluate the feasibility, safety, and immunological effects of intrathecal and
intravenous administration of autologous mesenchymal stem cells (MSCs)(also …
intravenous administration of autologous mesenchymal stem cells (MSCs)(also …
Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair—current views
DG Phinney, DJ Prockop - Stem cells, 2007 - academic.oup.com
Mesenchymal stem cells or multipotent stromal cells (MSCs) isolated from the bone marrow
of adult organisms were initially characterized as plastic adherent, fibroblastoid cells with the …
of adult organisms were initially characterized as plastic adherent, fibroblastoid cells with the …
Fat tissue: an underappreciated source of stem cells for biotechnology
JK Fraser, I Wulur, Z Alfonso, MH Hedrick - Trends in biotechnology, 2006 - cell.com
Adipose tissue can be harvested in large amounts with minimal morbidity. It contains
numerous cells types, including adipocytes, preadipocytes, vascular endothelial cells and …
numerous cells types, including adipocytes, preadipocytes, vascular endothelial cells and …
Adipose-derived stem cells differentiate into a Schwann cell phenotype and promote neurite outgrowth in vitro
PJ Kingham, DF Kalbermatten, D Mahay… - Experimental …, 2007 - Elsevier
Experimentally, peripheral nerve repair can be enhanced by Schwann cell transplantation
but the clinical application is limited by donor site morbidity and the inability to generate a …
but the clinical application is limited by donor site morbidity and the inability to generate a …
[HTML][HTML] Stem cell treatment of degenerative eye disease
Stem cell therapies are being explored extensively as treatments for degenerative eye
disease, either for replacing lost neurons, restoring neural circuits or, based on more recent …
disease, either for replacing lost neurons, restoring neural circuits or, based on more recent …
Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury
Transplantation of bone marrow-derived mesenchymal stromal cells (MSCs) into the injured
brain or spinal cord may provide therapeutic benefit. Several models of central nervous …
brain or spinal cord may provide therapeutic benefit. Several models of central nervous …
Mesenchymal stem cells for clinical application
L Sensebe, M Krampera, H Schrezenmeier… - Vox …, 2010 - Wiley Online Library
Mesenchymal Stem Cells/Multipotent Marrow Stromal Cells (MSC) are multipotent adult
stem cells present in all tissues, as part of the perivascular population. As multipotent cells …
stem cells present in all tissues, as part of the perivascular population. As multipotent cells …
BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury
P Lu, LL Jones, MH Tuszynski - Experimental neurology, 2005 - Elsevier
Bone marrow stromal cells (MSCs) constitute a heterogeneous cell layer in the bone
marrow, supporting the growth and differentiation of hematopoietic stem cells. Recently, it …
marrow, supporting the growth and differentiation of hematopoietic stem cells. Recently, it …