B cells in HIV infection and disease

S Moir, AS Fauci - Nature Reviews Immunology, 2009 - nature.com
In recent years, intense research efforts have been dedicated to elucidating the pathogenic
mechanisms of HIV-associated disease progression. In addition to the progressive depletion …

Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily

S Moir, A Malaspina, OK Pickeral… - The Journal of …, 2004 - rupress.org
Human immunodeficiency virus (HIV) infection leads to numerous perturbations of B cells
through mechanisms that remain elusive. We performed DNA microarray, phenotypic, and …

Perturbations in B cell responsiveness to CD4+ T cell help in HIV-infected individuals

S Moir, KM Ogwaro, A Malaspina… - Proceedings of the …, 2003 - National Acad Sciences
HIV infection induces a wide array of B cell dysfunctions. We have characterized the effect of
plasma viremia on the responsiveness of B cells to CD4+ T cell help in HIV-infected patients …

HIV-1, lipid rafts, and antibodies to liposomes: implications for anti-viral-neutralizing antibodies

CR Alving, Z Beck, N Karasavva… - Molecular membrane …, 2006 - Taylor & Francis
The human immunodeficiency virus type 1 (HIV-1) is an enveloped virus with a lipid bilayer
that contains several glycoproteins that are anchored in, or closely associated with, the …

Distinct systemic microbiome and microbial translocation are associated with plasma level of anti-CD4 autoantibody in HIV infection

W Xu, Z Luo, AV Alekseyenko, L Martin, Z Wan… - Scientific reports, 2018 - nature.com
Microbial signals have been linked to autoantibody induction. Recently, we found that
purified anti-CD4 autoantibodies from the plasma of chronic HIV-1-infected patients under …

Dysregulation of sphingolipid and sterol metabolism by ApoE4 in HIV dementia

RG Cutler, NJ Haughey, A Tammara, JC McArthur… - Neurology, 2004 - AAN Enterprises
Background: Polymorphisms in apolipoprotein E have been associated with worse
prognoses in numerous neurodegenerative conditions, including HIV dementia (HIVD) …

Antibodies against heat shock proteins and cholesterol in HIV infection

G Füst, Z Beck, D Bánhegyi, J Kocsis, A Bíró… - Molecular …, 2005 - Elsevier
This review summarizes data on the presence and function of different heat shock proteins
(Hsp) in the HIV virions and the infected cells. A 60 kD heat shock protein-like molecule is …

Anti-cholesterol antibodies in human sera

A Horváth, A Bı́ró - Autoimmunity Reviews, 2003 - Elsevier
In the last 30 years many research showed that high serum cholesterol level is a great risk
for the atherosclerosis. In recent years, it has become clear that the immune system has a …

Serum anti-cholesterol antibodies in chronic hepatitis-C patients during IFN-α-2b treatment

A Bíró, A Horváth, L Varga, E Nemesánszky… - Immunobiology, 2003 - Elsevier
Previously we detected more than 3 times higher anti-cholesterol antibody (ACHA) levels in
HIV positive patients compared to healthy individuals, however, this level significantly …

A closer look into the GL7 antigen: its spatio-temporally selective differential expression and localization in lymphoid cells and organs in human

A Balogh, M Ádori, K Török, J Matko, G László - Immunology letters, 2010 - Elsevier
The GL7 epitope was originally described as part of a late lymphocyte activation antigen
expressed in mouse and widely used since then as a marker of germinal center. Here we …