Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …

Neural stem cells in the adult mammalian brain are the source of new neurons that
contribute to complex sensory and cognitive functions. Most adult neural stem cells are …

In the adult rodent brain, neural stem cells (NSCs) persist in the ventricular-subventricular
zone (V-SVZ) and the subgranular zone (SGZ), which are specialized niches in which young …

Although the neurogenesis-enhancing effects of exercise have been extensively studied, the
molecular mechanisms underlying this response remain unclear. Here, we propose that this …

Adult hippocampal neurogenesis is the process by which new functional neurons are added
to the adult dentate gyrus of the hippocampus. Animal studies have shown that the degree of …

Neural stem cells (NSCs) generate neurons throughout life in the mammalian hippocampus.
However, the potential for long-term self-renewal of individual NSCs within the adult brain …

Background: The hippocampus is one of the sites in the mammalian brain that is capable of
continuously generating controversy. Adult neurogenesis is a remarkable process, and yet …

Astrocytes, the most abundant type of glial cells in the brain, play an important role in
preserving normal neural functions and mediating the pathogenesis of neurological …

The establishment of neuronal and glial networks in the brain depends on the activities of
neural progenitors, which are influenced by cell-intrinsic mechanisms, interactions with the …

Exercise is a simple intervention that profoundly benefits cognition. In rodents, running
increases neurogenesis in the hippocampus, a brain area important for memory. We …