Eudragit® polymers are polymethacrylates highly used in pharmaceutics for the
development of modified drug delivery systems. They are widely known due to their …

Background: In the era of pharmaceutical research and development, the most challenging
aspect is to enhance the physicochemical properties of drugs. Hot Melt Extrusion (HME) is a …

The present study aims are to develop general models based on Abraham solvation
parameters and Hansen solubility parameters to predict mesalazine solubility in cosolvency …

Hydrochlorothiazide (HTZ) is a potent thiazide diuretic that is used in the management of
hypertension. However, HTZ suffers from low and variable oral bioavailability owing to its …

Numerous hydrophobic compounds are important ingredients for drug discovery and
development. Hydrophobicity has been a major hurdle limiting the therapeutic efficacy of …

Objectives: Polylactic acid (PLA) and copolymer polylactic-co-glycolic acid (PLGA) are the
most versatile drug carriers for long acting release injectable (LAI) formulations for small …

The aim of this research was the preformulation and preliminary formulation studies of oral
gastro-resistant tablets containing 500 mg mesalazine. Increased compliance of the …

Crystal engineering is an integral part of the drug development research. Crystal forms can
modify the physicochemical properties of the parent drug molecule. The present work was …

5-Aminosalicylic acid (5-ASA) is a first-line defense drug used to treat mild cases of
inflammatory bowel disease. When administered orally, the active pharmaceutical ingredient …

Purpose: Oral drug delivery system has always been a preferred choice for the treatment of
peptic ulcer and gastroesophageal reflux diseases. Being a proton pump inhibitor …