Molecular mechanisms behind free radical scavengers function against oxidative stress

F Ahmadinejad, S Geir Møller… - Antioxidants, 2017 - mdpi.com
Accumulating evidence shows that oxidative stress is involved in a wide variety of human
diseases: rheumatoid arthritis, Alzheimer's disease, Parkinson's disease, cancers, etc. Here …

The role of MicroRNAs in environmental risk factors, noise-induced hearing loss, and mental stress

V Miguel, JY Cui, L Daimiel… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: MicroRNAs (miRNAs) are important regulators of gene expression and define
part of the epigenetic signature. Their influence on every realm of biomedicine is established …

Umbilical cord mesenchymal stromal cell-derived exosomes rescue the loss of outer hair cells and repair cochlear damage in cisplatin-injected mice

SCS Tsai, KD Yang, KH Chang, FCF Lin… - International Journal of …, 2021 - mdpi.com
Umbilical cord-derived mesenchymal stromal cells (UCMSCs) have potential applications in
regenerative medicine. UCMSCs have been demonstrated to repair tissue damage in many …

Expression and Regulatory Mechanisms of MicroRNA in Cholesteatoma: A Systematic Review

K Dżaman, K Czerwaty, TE Reichert… - International Journal of …, 2023 - mdpi.com
Cholesteatoma is a temporal bone disease characterized by dysfunctions of keratinocytes.
MicroRNAs (miRNAs) are evolutionary conserved noncoding RNAs that regulate mRNA …

MicroRNA-193b-3p regulates hepatocyte apoptosis in selenium-deficient broilers by targeting MAML1

T Liu, T Yang, Z Xu, S Tan, T Pan, N Wan… - Journal of inorganic …, 2018 - Elsevier
Selenium (Se) is an important nutritional element in the diet. Apoptosis is one of the
characteristic pathological changes in liver tissue resulting from Se deficiency. MicroRNA …

Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation

W Zhu, W Du, AP Rameshbabu… - Science translational …, 2024 - science.org
Mutations in microRNA-96 (MIR96) cause autosomal dominant deafness-50 (DFNA50), a
form of delayed-onset hearing loss. Genome editing has shown efficacy in hearing recovery …

[HTML][HTML] Genotype characterization and miRNA expression profiling in Usher syndrome cell lines

WA Tom, DS Chandel, C Jiang… - International Journal of …, 2024 - mdpi.com
Usher syndrome (USH) is an inherited disorder characterized by sensorineural hearing loss
(SNHL), retinitis pigmentosa (RP)-related vision loss, and vestibular dysfunction. USH …

Long-chain non-coding RNA UCA1 inhibits renal tubular epithelial cell apoptosis by targeting microRNA-206 in diabetic nephropathy

R Yu, Y Zhang, Z Lu, J Li, P Shi, J Li - Archives of Physiology and …, 2022 - Taylor & Francis
In this study, the inhibitory effect of long-chain non-coding RNA urothelial carcinoma
associated 1 (UCA1) on renal tubular epithelial cell apoptosis by targeting microRNA …

Therapeutic application of mesenchymal stem cells for cochlear regeneration

N Maharajan, GW Cho, CH Jang - in vivo, 2021 - iv.iiarjournals.org
Hearing loss is one of the major worldwide health problems that seriously affects human
social and cognitive development. In the auditory system, three components outer ear …

A genome-wide association study identifies novel loci of vertigo in an Asian population-based cohort

SP Chen, CL Hsu, TH Chen, LLH Pan… - Communications …, 2024 - nature.com
The contributing genetic factors of vertigo remain poorly characterized, particularly in
individuals of non-European ancestries. Here we show the genetic landscape of vertigo in …