Methods to study Drosophila immunity
C Neyen, AJ Bretscher, O Binggeli, B Lemaitre - Methods, 2014 - Elsevier
Innate immune mechanisms are well conserved throughout evolution, and many theoretical
concepts, molecular pathways and gene networks are applicable to invertebrate model …
concepts, molecular pathways and gene networks are applicable to invertebrate model …
How are arbovirus vectors able to tolerate infection?
One of the defining features of mosquito vectors of arboviruses such as Dengue and Zika is
their ability to tolerate high levels of virus proliferation without suffering significant pathology …
their ability to tolerate high levels of virus proliferation without suffering significant pathology …
Symbionts Commonly Provide Broad Spectrum Resistance to Viruses in Insects: A Comparative Analysis of Wolbachia Strains
J Martinez, B Longdon, S Bauer, YS Chan… - PLoS …, 2014 - journals.plos.org
In the last decade, bacterial symbionts have been shown to play an important role in
protecting hosts against pathogens. Wolbachia, a widespread symbiont in arthropods, can …
protecting hosts against pathogens. Wolbachia, a widespread symbiont in arthropods, can …
The Toll-Dorsal Pathway Is Required for Resistance to Viral Oral Infection in Drosophila
ÁG Ferreira, H Naylor, SS Esteves, IS Pais… - PLoS …, 2014 - journals.plos.org
Pathogen entry route can have a strong impact on the result of microbial infections in
different hosts, including insects. Drosophila melanogaster has been a successful model …
different hosts, including insects. Drosophila melanogaster has been a successful model …
Host adaptation is contingent upon the infection route taken by pathogens
Evolution of pathogen virulence is affected by the route of infection. Also, alternate infection
routes trigger different physiological responses on hosts, impinging on host adaptation and …
routes trigger different physiological responses on hosts, impinging on host adaptation and …
Functional Analysis of PGRP-LA in Drosophila Immunity
PeptidoGlycan Recognition Proteins (PGRPs) are key regulators of the insect innate
antibacterial response. Even if they have been intensively studied, some of them have yet …
antibacterial response. Even if they have been intensively studied, some of them have yet …
The route of infection determines Wolbachia antibacterial protection in Drosophila
V Gupta, RB Vasanthakrishnan… - … of the Royal …, 2017 - royalsocietypublishing.org
Bacterial symbionts are widespread among metazoans and provide a range of beneficial
functions. Wolbachia-mediated protection against viral infection has been extensively …
functions. Wolbachia-mediated protection against viral infection has been extensively …
High Anti-Viral Protection without Immune Upregulation after Interspecies Wolbachia Transfer
E Chrostek, MSP Marialva, R Yamada, SL O'Neill… - PLoS one, 2014 - journals.plos.org
Wolbachia, endosymbionts that reside naturally in up to 40–70% of all insect species, are
some of the most prevalent intracellular bacteria. Both Wolbachia w Au, naturally associated …
some of the most prevalent intracellular bacteria. Both Wolbachia w Au, naturally associated …
Comparative RNA-Seq analyses of Drosophila plasmatocytes reveal gene specific signatures in response to clean injury and septic injury
E Ramond, JP Dudzic, B Lemaitre - PloS one, 2020 - journals.plos.org
Drosophila melanogaster's blood cells (hemocytes) play essential roles in wound healing
and are involved in clearing microbial infections. Here, we report the transcriptional changes …
and are involved in clearing microbial infections. Here, we report the transcriptional changes …
Developmental arrest of Drosophila survival motor neuron (Smn) mutants accounts for differences in expression of minor intron-containing genes
Reduced levels of survival motor neuron (SMN) protein lead to a neuromuscular disease
called spinal muscular atrophy (SMA). Animal models of SMA recapitulate many aspects of …
called spinal muscular atrophy (SMA). Animal models of SMA recapitulate many aspects of …