Towards the optical cochlear implant: optogenetic approaches for hearing restoration
Cochlear implants (CI s) are considered the most successful neuroprosthesis as they enable
speech comprehension in the majority of half a million CI users suffering from sensorineural …
speech comprehension in the majority of half a million CI users suffering from sensorineural …
Multifunctional soft implants to monitor and control neural activity in the central and peripheral nervous system: a review
Z Fekete, A Pongrácz - Sensors and Actuators B: Chemical, 2017 - Elsevier
The development of neural implants is seeking minimally invasive approaches by utilizing
novel polymer substrates and integration concepts to interface the living tissue. In the recent …
novel polymer substrates and integration concepts to interface the living tissue. In the recent …
[HTML][HTML] High-density μLED-based optical cochlear implant with improved thermomechanical behavior
This study reports the realization of an optical cochlear implant (oCI) with optimized
thermomechanical properties for optogenetic experiments. The oCI probe comprises 144 …
thermomechanical properties for optogenetic experiments. The oCI probe comprises 144 …
μLED‐based optical cochlear implants for spectrally selective activation of the auditory nerve
Electrical cochlear implants (eCIs) partially restore hearing and enable speech
comprehension to more than half a million users, thereby re‐connecting deaf patients to the …
comprehension to more than half a million users, thereby re‐connecting deaf patients to the …
Multiscale photonic imaging of the native and implanted cochlea
D Keppeler, CA Kampshoff… - Proceedings of the …, 2021 - National Acad Sciences
The cochlea of our auditory system is an intricate structure deeply embedded in the temporal
bone. Compared with other sensory organs such as the eye, the cochlea has remained …
bone. Compared with other sensory organs such as the eye, the cochlea has remained …
[HTML][HTML] Cardiac pacing using transmural multi-LED probes in channelrhodopsin-expressing mouse hearts
CM Zgierski-Johnston, S Ayub, MC Fernández… - Progress in Biophysics …, 2020 - Elsevier
Optogenetics enables cell-type specific monitoring and actuation via light-activated proteins.
In cardiac research, expressing light-activated depolarising ion channels in cardiomyocytes …
In cardiac research, expressing light-activated depolarising ion channels in cardiomyocytes …
Chronic neural probe for simultaneous recording of single-unit, multi-unit, and local field potential activity from multiple brain sites
Objective. Drug resistant focal epilepsy can be treated by resecting the epileptic focus
requiring a precise focus localisation using stereoelectroencephalography (SEEG) probes …
requiring a precise focus localisation using stereoelectroencephalography (SEEG) probes …
[HTML][HTML] Devising a framework of optogenetic coding in the auditory pathway: Insights from auditory midbrain recordings
M Michael, BJ Wolf, A Klinge-Strahl, M Jeschke… - Brain Stimulation, 2023 - Elsevier
Cochlear implants (CIs) restore activity in the deafened auditory system via electrical
stimulation of the auditory nerve. As the spread of electric current in biological tissues is …
stimulation of the auditory nerve. As the spread of electric current in biological tissues is …
Towards optogenetic approaches for hearing restoration
Hearing impairment (HI) is the most frequent sensory deficit in humans. As yet there is no
causal therapy for sensorineural HI-the most common form–that results from cochlear …
causal therapy for sensorineural HI-the most common form–that results from cochlear …
[HTML][HTML] Towards the clinical translation of optogenetic skeletal muscle stimulation
Paralysis is a frequent phenomenon in many diseases, and to date, only functional electrical
stimulation (FES) mediated via the innervating nerve can be employed to restore skeletal …
stimulation (FES) mediated via the innervating nerve can be employed to restore skeletal …