Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

State-of-the-art proteomics-grade mass spectrometers can measure peptide precursors and
their fragments with ppm mass accuracy at sequencing speeds of tens of peptides per …

Mass spectrometry has transformed the field of cell signaling by enabling global studies of
dynamic protein phosphorylation ('phosphoproteomics'). Recent developments are enabling …

A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

Improvements in both liquid chromatography (LC) and mass spectrometry (MS)
instrumentation have greatly enhanced proteomic and small molecule metabolomic analysis …

Matrix assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a
powerful technology used to investigate the spatial distributions of thousands of molecules …

The evolution of mass spectrometry–based proteomic technologies has advanced our
understanding of the complex and dynamic nature of proteomes while concurrently …

Deregulated cellular signalling is a common hallmark of disease, and delineating tissue
phosphoproteomes is key to unravelling the underlying mechanisms. Here we present the …

Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …