[HTML][HTML] Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and …
Background Behavioural, cognitive, and pharmacological interventions can all be effective
for insomnia. However, because of inadequate resources, medications are more frequently …
for insomnia. However, because of inadequate resources, medications are more frequently …
Representation and extrapolation: evidence from clinical trials
This article examines the consequences and causes of low enrollment of Black patients in
clinical trials. We develop a simple model of similarity-based extrapolation that predicts that …
clinical trials. We develop a simple model of similarity-based extrapolation that predicts that …
ROB-ME: a tool for assessing risk of bias due to missing evidence in systematic reviews with meta-analysis
Various methods are available to help users assess whether selective non-publication of
studies or selective non-reporting of study results has occurred, but not its impact on a meta …
studies or selective non-reporting of study results has occurred, but not its impact on a meta …
Pharmacogenetics of anxiety and depression in Alzheimer's disease
R Cacabelos, JC Carril, L Corzo, R Pego… - …, 2023 - Taylor & Francis
Anxiety and depression coexist with cognitive impairment in Alzheimer's disease along with
other concomitant disorders (> 60%), which require multipurpose treatments …
other concomitant disorders (> 60%), which require multipurpose treatments …
[HTML][HTML] Machine learning approaches and non-linear processing of extracted components in frontal region to predict rTMS treatment response in major depressive …
E Ebrahimzadeh, F Fayaz, L Rajabion… - Frontiers in Systems …, 2023 - frontiersin.org
Predicting the therapeutic result of repetitive transcranial magnetic stimulation (rTMS)
treatment could save time and costs as ineffective treatment can be avoided. To this end, we …
treatment could save time and costs as ineffective treatment can be avoided. To this end, we …
[HTML][HTML] Evaluation of randomized controlled trials: a primer and tutorial for mental health researchers
Background Considered one of the highest levels of evidence, results of randomized
controlled trials (RCTs) remain an essential building block in mental health research. They …
controlled trials (RCTs) remain an essential building block in mental health research. They …
[HTML][HTML] Reporting bias in clinical trials: Progress toward transparency and next steps
M Mitra-Majumdar, AS Kesselheim - PLoS Medicine, 2022 - journals.plos.org
Reporting bias in clinical trials: Progress toward transparency and next steps | PLOS Medicine
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The involvement of serotonin in major depression: nescience in disguise?
Moncrieff and colleaguesL umbrella review [1] offers an opportunity to reflect on the
'Serotonin hypothesisL of depression serendipitously developed 50 years ago. The notion …
'Serotonin hypothesisL of depression serendipitously developed 50 years ago. The notion …
Adoption of world health organization best practices in clinical trial transparency among European medical research funder policies
T Bruckner, F Rodgers, L Styrmisdóttir… - JAMA Network …, 2022 - jamanetwork.com
Importance Research funders can reduce research waste and publication bias by requiring
their grantees to register and report clinical trials. Objective To determine the extent to which …
their grantees to register and report clinical trials. Objective To determine the extent to which …