Decellularization of natural tissues to produce extracellular matrix is a promising method for
three-dimensional scaffolding and for understanding microenvironment of the tissue of …

Current methods to differentiate cardiomyocytes from human pluripotent stem cells (PSCs)
inadequately recapitulate complete development and result in PSC-derived cardiomyocytes …

The generation of 3D tissue constructs with multiple cell types and matching mechanical
properties remains a challenge in cardiac tissue engineering. Recently, 3D bioprinting has …

The extracellular matrix (ECM) is a dynamic structural network that provides a physical
scaffolding, as well as biochemical factors that maintain normal tissue homeostasis and thus …

Cellular senescence is a complex cell state that can occur during physiological ageing or
after exposure to stress signals, regardless of age. It is a dynamic process that continuously …

Although the extracellular matrix (ECM) plays essential roles in heart tissue engineering, the
optimal ECM components for heart tissue organization have not previously been elucidated …

Ischemic cardiomyopathy (ICM) affect millions of patients globally. Decellularized
extracellular matrix materials (dECM) have components, microstructure and mechanical …

Tissue formation and healing both require cell proliferation and migration, but also
extracellular matrix production and tensioning. In addition to restricting proliferation of …

Current biomarkers for myocardial infarction (MI) diagnosis are typically late markers
released upon cell death, incapable of distinguishing between ischemic and reperfusion …

The ability to reprogram patient-derived-somatic cells to IPSCs (Induced Pluripotent Stem
Cells) has led to a better understanding of aging and age-related diseases like Parkinson's …