Background Update diagnostic methods play essential roles in dealing with the current
global malaria situation and decreasing malaria incidence. Aim Global malaria control …

▪ Abstract Hemoglobin degradation in intraerythrocytic malaria parasites is a vast process
that occurs in an acidic digestive vacuole. Proteases that participate in this catabolic …

Severe falciparum malaria is one of the most lethal parasitic infections in the world and is
responsible for more than one million deaths in African children per year. Changes to …

Malaria is still a major cause of severe disease which is responsible for millions of deaths,
mostly in children under 5 years old, in tropical countries, especially sub-Saharan Africa …

ABSTRACT We compared interleukin-12 (IL-12) and other cytokine activities during and
after an acute clinical episode in a matched-pair case-control study of young African children …

Neutrophils are abundant in the circulation and are one of the immune system's first lines of
defense against infection. There has been substantial work carried out investigating the role …

Malaria causes significant morbidity and mortality worldwide, including countries with mainly
imported malaria. In developing nations, scarce resources lead to inadequate diagnostic …

The role of proinflammatory cytokine production in the pathogenesis of malaria is well
established, but the identification of the parasite products that initiate inflammation is not …

Iron is essential for both host and pathogen, and complex systems of acquisition and
utilization have evolved in competition. Our increasing knowledge of the basic mechanisms …

Background Routine antipyretic therapy in children with infectious diseases has long been
the source of controversy. Each year, in addition to antimalarial medication, millions of …