Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …

Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are two different
entities sharing common clinical and physio-pathological features, with insulin resistance …

Obesity is the accumulation of abnormal or excessive fat that may interfere with the
maintenance of an optimal state of health. The excess of macronutrients in the adipose …

Epidemiological studies have documented a high incidence of diabetes in hypertensive
patients. Insulin resistance is defined as a less than expected biologic response to a given …

Hypertension is a highly prevalent condition with numerous health risks, and the incidence
of hypertension is greatest among older adults. Traditional discussions of hypertension have …

Background Insulin resistance (IR) is one of the major hallmark for pathogenesis and
etiology of type 2 diabetes mellitus (T2DM). IR is directly interlinked with various …

Impaired insulin-mediated suppression of hepatic glucose production (HGP) plays a major
role in the pathogenesis of type 2 diabetes (T2D), yet the molecular mechanism by which …

Stressors are imminent or perceived challenges to homeostasis. The stress response is an
innate, stereotypic, adaptive response to stressors that has evolved in the service of …

Hypertension is a complex condition and is the most common cardiovascular risk factor,
contributing to widespread morbidity and mortality. Approximately 90% of hypertension …

Whereas in most cases a fatty liver remains free of inflammation, 10%‐20% of patients who
have fatty liver develop inflammation and fibrosis (nonalcoholic steatohepatitis [NASH]) …